Question

1 1pt. Why is herpesvirus only transmitted via direct or intimate contact with mucous membranes or body fluids and never from toilet seats or fomites? 21 pt. Once you are infected with herpes virus, you will never get rid of it. Why does this virus remain in your body? 3 1pt. What is one reason why condoms only reduce the rate of transmission by 50% ? The way Valtrex works Two more Valacyclovir (Valtrex) 4) DNA is not 3) phosphates are 1) valine and 2) acyclovir becomes made monophosphorylated acyclovir added 1) In intestines, host enzymes break down valacyclovir to valine and acyclovir 2) Acyclovir is taken up by all cells; but only in virus infected cells a viral enzyme (thymidine kinase) works to add a phosphate. Acyclovir binds VERY well to this virus enzyme, more so than any cellular/host enzyme. 3) Next, a host cell enzyme adds more phosphates; now acyclovir is an analog - looks like a guanine nucleotide. 4) Many of these analogs are made and they competitively inhibit the DNA polymerase. If the analog is inserted into new DNA, this completely stops DNA from being made. 5) Since the virus is replicating in the host cell at a faster rate than the cell, the virus numbers are decreased. 4 1pt. each: TRUE or FALSE a. Transmission of herpes virus occurs only when lesions are present. b. Most herpes virus infections are not severe except in the case of neonates where it can be fatal. c. HSV infects epithelial cells of mucous membranes only, it is very limited in to the type of tissue it can infect. d. If you have one partner you do not have a chance of obtaining an HSV infection. It is only if you have 2 or more partners when transmission occurs. e. Valtrex has specific toxicity for herpes virus because the drug binds directly to a viral enzyme, host metabolic processes are not involved. 51 pt.each a. Valtrex will never "cure" a person of herpes- explain why b. From the article: She (Diane) has sex with him (Bill) with birth control pills instead of condoms. .. Explain how this is evidence that Diane is not the sharpest knife in the drawer

1-5 please and thank you.

Answer 1

1. Herpes virus does not survive for long out side the host. That is why it is not transmitted by toilet seats or fomites.

2. Herpes virus does not cause symptoms all the time. It is mostly quiet in the body. It hides in the root ganglion system (neurons) which is not reachable by any drug for treatment. So it is very difficult to eliminate.

3. Herpes spreads through other means also not just by vaginal sex. It can spread through skin if your partner has oral herpes or genital herpes. Through sores on the body also they can spread. That is why condom usage has only 50% reduction in the spread of the disease.