Question

Match the following plasma proteins with their function?

clotting ,enzyamtic reaction, oncotic pressure

1.Fibrinogen, prothrombin-

2.Alanine aminotransferase, aspartate aminotransferase -

3.Albumin, prealbumin, transferrin, lipoproteins, globulins-

subject -nutrition

Answer 1

CLOTTING : fibrinoen and prothrombin

Blood clotting is the process of forming a blood clot. It follows the development of a platelet plug as part of hemostasis and is essentially a continuation of the platelet phase. Blood clotting does not just start immediately after the formation of a platelet plug but is rather the consequence of a series of steps that commences with vessel injury. The clotting process involves 12 clotting factors (11 different specialized chemicals and calcium) which act on each other to lead to clot formation and this is known as the coagulation cascade.
Prothrombin is one of the proteins in constant circulation in the blood. It is manufactured by the liver and requires vitamin K.If the liver does not produce thrombin for one or two days, blood clotting is compromised. The Prothrombin Activator converts prothrombin into thrombin. Thrombin is essentially an enzyme that then converts fibrinogen into fibrin.
Fibrinogen is a protein formed by the liver. When thrombin acts on it, fibrinogen is converted into a lighter protein known as fibrin. Many fibrin molecules can attach to each other to form long fibrin strands. These strands are then laid down over the platelet plug (second phase of hemostasis) to secure the platelets, trap blood cells and more firmly seal the area. This is essentially a blood clot.

ENZYMATIC REACTION: Alanine aminotransferase and Aspartate aminotransferase

Aminotransferase (AST) is an enzyme that’s present in various tissues of your body. An enzyme is a protein that helps trigger chemical reactions that your body needs to function.
Alanine aminotransferase (commonly abbreviated ALT) is a type of enzyme which along with AST works for the same cause.

ONCOTIC PRESSURE: albumin, prealbumin, transferin, lipoproteins, globulins

Albumin is a visceral protein and has a large body pool, distributed between the vascular and interstitial spaces. Only 5 % is synthesized daily. Albumin functions as a carrier protein, and assists in maintaining oncotic pressure.