The strength of an acid can be determined by different methods among them pKa is one of the method .Lower the pKa volue of a compound more stronger acidic the compound will b and vice versa.
Among the 5 compouds the compound D will be having lower pKa value and stronger acid it will be,becoz in D compound there is CCl3 group which is having more electron drifting power towards itself and hydrogen will leave easily as proton .
so option D is correct option
4. Which of the following structures has the lowest pka? он он он HN
Rank the following structures from highest acidity (lowest pKa value) to lowest acidity (highest pKa value). The acidic hydrogen is indicated in red in each structure. Rank the following structures from highest acidity (lowest pKa value) to lowest acidity (highest pKa value). The acidic hydrogen is indicated in red in each structure.
organic chemistry. which of the following compounds has the lowest pka? 4. Which of the following compounds has the lowest pK? . .་ ་ ་ ་ ་ ་
6.4 Consider the following reactions below: OH А + H2NCH3 4. O B ОН + HN(CH3)2 A. a) b) Draw the structures of the products formed Which reaction takes place faster? Give reasons for your choice.
4... Which structure or structures represent the enantiomer of the following molecule? он OCH он он он он H3COli OCH Осн; mOCH Br Br Brl I IV II III a l d. IV e I and V b II C.ID
Please answer all. Just need A,B,C or D 2. (01') Which proton has the lowest pKa value (This is Elvitegravir an HIV drug)? На CI O2Hd A) Ha B) Hb C) Hc D) Hd 3. (Q1) Which is the major product in this reaction? 1) Sia28H-THF 2) H202, NaOH C) D) но он 4. (a1') What is the hybridization of the nitrogen atom in the following structure? NH A) sp B) sp C) sp D) sp
Rank the following compounds in order of increasing pKa, entering a 1, 2, 3, or 4 next to each structure, with 1 for lowest pKa and 4 for highest pKa Rank the following compounds in order of increasing pKa, entering a 1, 2, 3, or 4 next to each structure, with 1 for lowest pKa and 4 for highest pKa Cl OH он CI H CI CI
List the following carboxylic acids in order of output of pKa (1 = lowest pKa ... 4 = highest pKa) Explain the factors that contribute to this reactivity trend.
27) The structures and pKa values of pyridinium, triethylammonium, and diisopropylammonium ions are provided pyridinium ion pKa 5.25 triethylammanium ion pKa 10.75 diisopropylammonium ion pKa 11.05 a. Which is the strongest acid pyridinium, Et3NH or iPr2NH2? b. Which is the strongest base pyridine, NEt3 or iPr2NH? 28) Given the structures of oseltamivir, isotretinoin, propofol and terbinafine, which is the most polar and hence most water soluble drug? O, HN NH2 COOH isotretinoin oseltamivir (Tamiflu) propofol (Diprivan) terbinafine (Lamisil) (Accutane)
36. Calculate the pl and identify which structure is at isoelectric point H.N -ċ-COOH pka HN - ċ-Coo- pkar H.N-C-COO CH соон COOH COO- pKa, HN - C-COO- CH CH 9.8 coo-
how many stereocenters are present? The following structure contains stereocenters. он он но HN