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N alt 5. In the synthesis of Camptothecin, a potent antitumor and antileukemic agent isolated from the stem wood of a Chinese
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Mechanismi N-COREL N-CORET T1 coget COEE O 9 [ N-(02E2 G ON-COREE I LI-I COREL I-28 -Co2Et BO OH & 6H2 gic N-COLER -C0227 N1. First 3 step are known as enamine synthesise, in which amine and ketone will form enamine.

2. Then lonepair of nitrogen involve and enamine will attack on aldehyde followed by dehydration.

3. Finally ring will go aromatisation to get our desired product.

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