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When an activator protein interacts with a mediator protein, how does it affect the function of...

When an activator protein interacts with a mediator protein, how does it affect the function of RNA polymerase?

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  • Mediator acts as a coactivator. It is a protein which interacts with preinitiation complex. Preinitiation complex is composed of RNA polymerase and basal transcription factors.
  • To stabilize this Complex and to initiate transcription, mediator binds to this preinitiation complex.

    Mediator sends signal to transcription factors so as to to stabilize the complex. It stabilizes the RNA transcript formed after transcription.
  • . It causes loops in chromatin so as to bring together the distantly located genes and regulatory region so that they can interact and undertake transcription.

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