Homework Answers
18) False, The receptors on the surface of B cells (BCRs) can bind to soluble antigens, while T cell receptors (TCRs) can only recognise an antigen when it is complexed with major histocompatibility complex (MHC) molecules on the surface of other cell
19) True, IgM is not only the first class of antibody to appear on the surface of a developing B cell.In its secreted form, IgM is a pentamer composed of five four-chain units, giving it a total of 10 antigen-binding sites.
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18- True or False A T cell receptor consists of an alpha and beta chain attached...
If the beta chain successfully (productively) rearranged, produced a functional pre T cell receptor and the alpha chain...
If the beta chain successfully (productively) rearranged, produced a functional pre T cell receptor and the alpha chain now begins to rearrange, can the cell still differentiate into a gamma/delta T cell? If yes or no, why?
The T cell receptor repertoire is greater than that of the B cell repertoire of unique...
The T cell receptor repertoire is greater than that of the B cell repertoire of unique receptors for all of the following reasons EXCEPT: a greater number of diversity segments that can be joined a greater number of joining segments that can be joined a greater number of V segments that can be recombined greater junctional diversity Which of the following is incorrectly matched with its function in the T cell receptor complex? Zeta ; signal transduction upon TCR activation...
True or False: Chimeric antigen receptor (CAR) T cells are cells that have been retrovirally transduced...
True or False: Chimeric antigen receptor (CAR) T cells are cells that have been retrovirally transduced with a tumor- specific T-cell receptor in order to treat a leukemia.
20. Defective function of which of the following proteins will result in failed antigen presentation to...
20. Defective function of which of the following proteins will result in failed antigen presentation to CD8 T cells? a. HLA-DM b. TAP c. Cathepsins d. CD1d 21.True or False: An antibody proteolytically cleaved by pepsin yields a fragment with higher avidity to the cognate antigen than an antibody cleaved by papain. a. True b. False 22.The structure recognized by an antibody (that is, the epitope) is the ________ and the regions of the antibody with significant sequence variation are...
If DNA rearrangement occurs within the T cell receptor α-chain, then _____________. Group of answer choices...
If DNA rearrangement occurs within the T cell receptor α-chain, then _____________. Group of answer choices A. the γ-chain locus is permanently deleted from the chromosome B. coexpression of α and γ is observed in mature T cells C. the δ-chain locus is permanently deleted from the chromosome D. coexpression of α and δ is observed in mature T cells
If DNA rearrangement occurs within the T cell receptor α-chain, then _____________. Group of answer choices...
If DNA rearrangement occurs within the T cell receptor α-chain, then _____________. Group of answer choices A. the γ-chain locus is permanently deleted from the chromosome B. coexpression of α and γ is observed in mature T cells C. the δ-chain locus is permanently deleted from the chromosome D. coexpression of α and δ is observed in mature T cells
18. Would you guess cellulose (which most animals cannot break sown) consists of alpha or beta...
18. Would you guess cellulose (which most animals cannot break sown) consists of alpha or beta links? 19. Given and abbreviated form of a molecule of cholesterol below, draw an "unabbreviated" molecule of cholesterol. H H HO 20. What kind of organic compound is glycerol? (Hint: look at the functional groups present) 21. Constructa monoglyceride (make the fatty acid up) via dehydration synthesis: (be sure to show the reaction, use chemical symbols format) de.. T
Which of the following statements is (are) true of a T cell that expresses two α chains (and thus...
Which of the following statements is (are) true of a T cell that expresses two α chains (and thus two different T-cell receptors) as a result of ineffective allelic exclusion of the α chain during rearrangement? There will be two unique TCRs on the surface of this T cell. Engaging either of the T-cell receptors on MHC molecules of the thymic epithelium will result in positive selection. If either T-cell receptor binds strongly to self-peptide presented by self-MHC molecules, the...
Immunology Help 1) Expression of functional beta chain protein signals that a thymocyte has successfully reached...
Immunology Help 1) Expression of functional beta chain protein signals that a thymocyte has successfully reached what stage of development? A The pro-T cell stage B The pre-T cell stage C The double-negative stage D The double-positive stage E The single-positive stage 2) Which one of the following types of antibodies is least likely to be found in normal lymph fluid? A IgA B IgD C IgE D IgG E IgM 3) Which CDR is found closest to the center...
Which of the following may be false? a. alpha + beta 1 b. power + beta 1 Power is defined as a. t...
Which of the following may be false? a. alpha + beta 1 b. power + beta 1 Power is defined as a. the probability of rejecting Ho if Ho is false b. the probability of accepting Hy if Hy is true c. the probability of rejecting Ho if Ho is false and the probability of accepting c. 1- power beta d. 1- beta power H, if H is true d. the probability of rejecting Ho if Ho is true Pnulis...
18. Would you guess cellulose (which most animals cannot break sown) consists of alpha or beta links? 19. Given and abbreviated form of a molecule of cholesterol below, draw an "unabbreviated" molecule of cholesterol. H H HO 20. What kind of organic compound is glycerol? (Hint: look at the functional groups present) 21. Constructa monoglyceride (make the fatty acid up) via dehydration synthesis: (be sure to show the reaction, use chemical symbols format) de.. T
Which of the following may be false? a. alpha + beta 1 b. power + beta 1 Power is defined as a. the probability of rejecting Ho if Ho is false b. the probability of accepting Hy if Hy is true c. the probability of rejecting Ho if Ho is false and the probability of accepting c. 1- power beta d. 1- beta power H, if H is true d. the probability of rejecting Ho if Ho is true Pnulis...
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