What is the dose in grams for high dose methotrexate 5 g/m2 is for a child...

Question

Question

What is the dose in grams for high dose methotrexate 5 g/m2 is for a child who weighs 66 lb and is 47.2 inches in height?

Answer 1

Answer #1

According to Du Bois formula for calculating BSA (Body Surface Area) = 0.007184 * W^0.425 * H^0.725

where W is the weight in Kg and H the height in cm.

Given, Weight of the child = 66 lb

To convert lb to Kg, we divide the lb by 2.205: 66/2.205 = 29.9 Kg

Height = 47.2 inches.

1 inch = 2.5 cm. Therefore , 47.2*2.5 = 118 cm.

BSA of the child = 0.007184* 29.9^0.425 * 118^0.725

= 0.007184* 4.27* 31.8

= 0.975 m²

Now, for a dosage of 5 g/ m2, the amount of methotrexate to be administered to the child would be : 0.975*5 = 4.875 g.

Answer 2

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