Compare the results from ClustalOmega and T-Coffee. Are the alignments from both programs the same? If not,...
Compare the results from ClustalOmega and T-Coffee. Are the alignments from both programs the same? If not, where do they differ? Which alignment would you tend to believe and why?
Clustal omega (scientific name):
T coffee(common name):
Homework Answers
The alignment accuracy is much higher in case of T-Coffee as compared to the accuracy of alignment generated by Clustal Omega.
The alignments from both the programs are different.
Alignment of maximum 100 sequences is possible by T-Coffee but
Clustal Omega has the capability of aligning 190,000
sequences.
The main algorithm of Clustal Omega is Hidden Markov Model whereas
the main algorithm of T-Coffee is consistency.
The alignment produced by Clustal Omega is much better as it can
align large sequences within few hours time on a single
processor.
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