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substances activate neutrophils?

substances activate neutrophils?
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Answer- Neutrophils are type of white blood cells that provide immunity to the body, they release chemicals called cytokines. They are the first molecule to come at the site after bacterial infection. They perform phagocytosis of the foreign molecule, chemotaxis, granulation. There are certain chemical substances required to activate the neutrophils.

There is a chemical substance called P substance that is a putative mediator of the nurogenic inflammation, this chemical substance is a potential regulator that helps in the activation of the neutrophil.  

Certain enzymes also help in the activation of neutrophils in the bodym enzymes like  myeloperoxidase, elastase, acid hydrolases, some cationic proteins and bacterial substrates also activates the pathway of neutrophils. Other enzymes include lysozyme, alkaline phoshatase, etc also play an important role in the defense mechansims that would help in providing immunity and preventing the invasion of microorhganisms.

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