Draw the chemical structure for malonyl-CoA (abbreviate “CoA” in your response).
Malonyl means derivative of malonic acid
malonic acid is nothing but dicarboxylic acid separated from one CH2 group
Draw the chemical structure for malonyl-CoA (abbreviate “CoA” in your response).
Provide the structure of the macrolide (acetyl-CoA + 3 x malonyl-CoA) corresponding to the following modules: AT-ACP-KS‐AT-KR-ACP-KS‐AT-ACP-KSAT-KR-ACP-KS-AT-ACP-TE.
You have made malonyl-CoA from marked CO2 and unmarked acetyl-CoA. Then you are using this malonyl-CoA to synthetized a C12:0 fatty acid. The final product will be radioactive at which carbons?
(a) If [2-14C-2-3H]acetyl-CoA (see the left figure above) and an
excess of unlabeled malonyl-CoA are added as substrates, how many
3H atoms are incorporated into every molecule of palmitate, and
what are their locations? How many 14C atoms are incorporated and
what are their locations?
(b) If unlabeled acetyl-CoA and an excess of
[1,3-14C-2-3H]malonyl-CoA (see the right figure above) are added as
substrates, how many 3H atoms are incorporated into every molecule
of palmitate, and what are their locations? How...
In the liver, which of the following enzymes is inhibited by malonyl CoA? A: fatty acid synthase, B: Acetyl CoA carboxylase, C: CPT-1, D: Hormone sensitive lipase
How does malonyl-CoA effect fatty acid oxidation? Why is this important?
(c) Will low malonyl CoA concentrations stimulate of inhibit ketogenesis? Explain your answer? Sal lae konstrasies van maloniel KoA ketogenese stimuleer of inhibeer? Verduidelik jou antwoord? 151
(c) Will low malonyl CoA concentrations stimulate of inhibit ketogenesis? Explain your answer? Sal lae konstrasies van maloniel KoA ketogenese stimuleer of inhibeer? Verduidelik jou antwoord? 151
If you wanted to know the concentration of malonyl-coA in solution, detail a standard addition procedure you would use to determine its concentration. A simple step by step process.
Discuss the metabolic importance and implications of malonyl CoA functioning as a negative allosteric regulator of carnitine palmitoyl transferase-1 (CPT-1; also known as as carnitine acyltransferase-1 or CAT-1)? (Explain and answer thoroughly)
Please explain your answer
Consider the step shown below. Up to this point, How many actetyl-CoA molecules were needed (including those that became malonyl-CoA)? How many malonyl-CoA molecules were needed? How many NADP:H molecules were needed?
Draw a Lewis structure for the molecule below, showing all lone
pairs. You may abbreviate any methyl groups as CH3
CH3(CH2),C(OH)2CH2C1