Question

11 Review Part B The genome of an organism consists of approximately 1.9 x 10° base pairs. DNA synthesis occurs at a rate of 40 base pairs per second. In the early embryo, the entire genome is replicated in 5 minutes. If there are 1.9 x 10° bases in the genome, and 24000 bases can be synthesized in 5 minutes, approximately how many bidirectional origins of synthesis are required to accomplish this feat? • 3958 0 7917 0 39583 79167 395833 0 791667 Submit Previous Answers Request Answer X Incorrect; Try Again; One attempt remaining

Answer 1

replication starts at the origin of replication and replication fork is bidirectional, 24000 bases are replicated in 5 minutes so the bidirectional replication fork replicates 48000 bases in 5 minutes so

number of origin of replications= total number of bases/ bases replicated in 5 minutes

= (1.9 $\times$ 10^9)/48000

= 39583.33

so the answer is 39583