Question

Return to Site (3 of 5) Using the data shown in the graph below determine which statement is correct. 100 0 Kd Kd 10 LI (uM) O The protein shown in binding curve B has a greater affinity for it's ligand as compared to the protein shown in binding curve A. OIf the IL] were 1 uM the percent saturation of A would be greater than B. O The percent saturation of A is expected to be greater than B at all [L]. O B has a lower affinity for its ligand, relative to A, and is therefore never expected to reach 100% saturation. 0 If [L] were to double it is expected that Y would also double at all points along the curve.

Answer 1

Ans : B has a lower affinity for its ligand , relative to A and is therefore never expected to reach 100% saturation.

The curve in right i.e. B has lower affinity for its ligand , due to which it dissociates easily , and hence has a lower percent dissociation , whereas the curve on left , i.e. A curve has higher affinity towards its ligand , and hence lesser percent saturation.