Organic Chemistry 4. Below are two molecules, B and C. Explain the differences in pKa of...
please thoroughly explain Phentolamine What is the most dominant species at pH 7.4? pka = a > H+ + НАС Verapamil pka = pKa = > H K H₃ C CH₃ → H CH,CO háchoenen OCH HCO OCH3 For each: Give the functional group name, hybridization and acidity (Acidic, Basic or Neutral) of the circled atoms •Give the likely conjugate acid form in water •Estimate the pka of circled atoms •Which one is the stronger base (blue circle) 121
Q.1. Draw the conjugate base or conjugate acid of the following species Conjugate Acid Conjugate Base a) OH Sb) ? CH3NH2 c) HO d) ? SO- Q.2. ) Circle the most acidic proton and cross out the least acidic protons among the shown hydrogen atoms in the following molecules. NO H NH2 O-H Η Η CH3 OH -SC-H Н" Q.3. Circle the most acidic compound and cross out the least acidic compound in each set. ou la olagla ОН OH...
4. Predict the ED geometry and bond angles around the indicated atoms in the molecules below. NOTE: LONE PAIRS ARE NOT SHOWN. H O For each of the following molecules, draw the wedge-and-dash representation and name the shape of the molecule. Note that in each molecule, N is the central atom. A. NO2 5. B. N2O C. NO-CI D. NH2
25,26,27 Select the stronger acid from the following molecules. O al door Oblon Oc) OH d) NH2 The pka of acetic acid ( ) is 4.75. What is the most likely pka of trifluoroaceti HEC OH acid ( i lon )? FC a) 0.23 b) 7.00 c) 5.80 d) 4.75 Which of the identified protons on the following molecule is the least acidic? А H B CHO OH D a) A Ob) в Occ d) D
all questions o orale a. Underline the most acidic hydrogens in each of the molecules. b. Rank the molecules above in order of increasing acidity (least acidic to most acidic). a. b. III, II, II, III, I d. II, 1, 5. Nitroethane [CH3CH, NO, PK, 8.6) is a much stronger acid than ethane (CH,CH.PK, 60). Explain. Consider the reaction below to answer the following question(s). pk = 26 pk = 40 0 L : Lit L H . YHLUN -...
Consider the indicated protons in the molecules shown below. Circle the molecule with the lower pK, and explain your choice with an appropriate drawing. NH ZE OH оме Но, . Meo b) Ho Ho (Rationalize with a one sentence explanation.) d) Rank the following molecules in order from least acidic to most acidic. Rationalize your choice with an appropriate drawing.
Biochemistry 4. The ionization of p-nitrophenol is shown below (pKa = 7.0): NO2 он weak acid conjugate base a. (4 points) Identify the weak acid and conjugate base. b. (4 points)At pH 7, what are the relative concentrations of ionized and un-ionized p- nitrophenol? c. (4 points)If enough concentrated hydrochloric acid is added to a solution of p-nitrophenol to lower the pH from 7 to 5, what will happen to the relative concentrations of the ionized and un-ionized forms? d....
IV) Acid/Base Reaction - Answer the next few questions about Molecule B, shown below. a) Circle the terms that correctly describe the molecule. H-bond acceptor dextrorotatory contains ketone racemic has enantiomer H-bond donor Molecule B [a] = -27.8° optically active contains aldehyde levorotatory b) Molecule B can react with another molecule in an acid/base reaction (shown below). olgan In the spaces provided, please do the following: i) Draw the structure of the missing molecule in the space provided. ii) Circle...
nust list A B C and what anaswers are Identify the molecules or ions below as Lewis acids, Lewis bases, or neither. If there is more than one possible site in the molecule/ion, focus on the central or the charged atom. 2 H₃C-P CH₂ CHE Lhyvis acid Lewis base neither NH3 Submit Answer Try Another Version ttempts remaining
Need number 2 and number 4 a and b answered The following compounds are drawn in their acidic forms, and their pK, values are given. Draw the form in which each compound will predominate in a solution with pH 8. CH COOH pka 4.8 CH CH2OH pKa = 15.9 CH OH pKa =-2.5 CH,CH2NH pka 11.2 a. What is the conjugate base of NH? A b. What is the conjugate base of H 0? c. What is the conjugate acid...