The Transcriptome of humans shows that (select all that apply): A. Approximately 2% of the genome...
The Transcriptome of humans shows that (select all that apply):
| A. |
Approximately 2% of the genome is transcribed |
|
| B. |
Protein coding genes represent the vast majority of the total genome sequence that is transcribed |
|
| C. |
A large number of non-protein coding sequences are transcribed |
|
| D. |
Total transcription changes over time in embryonic stem cells |
Homework Answers
Option A, C, D.
Approximately only 2% of the genome is transcribed which accouts for 20,000 to 30,000 gene. Approximately 98% of the human genome does not get transcribed or code for anthing and are termed as non-coding DNA. Vast majority of the human genome represent the non-coding sequence and not the protein coding gene.
A large number of non-protein coding sequence are transcribed such as tRNA, rRNA and other regulatory RNA such as siRNA, miRNA,etc.
Total transcription changes over time in embryonic stem cells. It is because when ESC differentiate in to different cells the tissue specific genes are only transcribed in those cells.
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