Question

The diagram below shows two stretches of DNA in the genome of an imaginary eukaryotic cell. The top stretch of DNA includes the fantasin gene, along with its promoter and one of its enhancers. The bottom stretch of DNA includes the imaginin gene, its promoter, and one of its enhancers. The slash marks (//) indicate that more than 1,000 nucleotides separate the promoter and enhancer of each gene

Which statements about the regulation of transcription initiation in these genes are true?
Select all that apply.

1) Control elements A, B, and C are proximal control elements for the fantasin gene.
2) The fantasin gene and the imaginin gene have identical enhancers.
3) Both the fantasin gene and the imaginin gene will be transcribed at high levels when activators specific for control elements A, B, C, D, and E are present in the cell.
4) Control elements C, D, and E are distal control elements for the imaginin gene.
5) The imaginin gene will be transcribed at a high level when repressors specific for the imaginin gene are present in the cell.
6) The fantasin gene will be transcribed at a high level when activators specific for control elements A, B, and C are present in the cell.
7) Both the fantasin gene and the imaginin gene will be transcribed at high levels whenever general transcription factors are present in the cell.

Answer 1

The true statements about the regulation of transcription initiation in these genes are as follows: . Control elements C, D, and E are distal control elements for the imaginin gene Both the fantasin gene and the imaginin gene levels when activators specific for control elements A, B, C, D, and E are present in the cell will be transcribed at high The fantasin gene will be transcribed at a high level when activators specific for control elements A, B, and C are present in the cell Thus, the correct options are (4), (6) and (7)