Question

1. The plaques seen in Alzheimer's Disease contain peptides that come from which protein?

A. Beta secretase B. Tau protein C. Amyloid Precursor protein D. Huntingtin protein E. Microtubule Associated protein

2. Mutations in presinilin 1 and 2 are associated with ____________

A. Frontotemporal Dementia

B. Vascular Dementia

C. the familial form of Alzheimer's Disease

D. Lewy Body Dementia

E. the sporadic form of Alzheimer's Disease

3. What role does Apolipoprotein E (APO E) play in Alzheimer's Disease?

A. It contributes to production of amyloid-beta by being part of gamma-secretase

B. It's involved in clearing of beta-amyloid from the brain

C. It plays a role in the immune system of the brain by trapping bacteria, yeast and fungus

D. It's involved in clearing of neurofibrillary tangles from the brain

4. A patient with Alzheimer's disease has no recollection of meeting a friend a few days earlier. What is the most likely explanation for this?

A. Amyloid plaques in the visual areas of the brain

B. expansion of the ventricles in the cerebral hemispheres

C. Neurofibrillary tangles in the frontal lobe

D. Neuronal death in the hippocampus

Answer 1

1-C-Amyloid deposits

2-C-Familial forms of Alzhemiers disease

3-A-It contributes in the production of beta amyloid by being a part of gamma secretase.

4-B,D Expansion of ventricular cavities and Neuronal death in hippocampus