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28. Which intermediate is not on the mechanistic pathway directly leading to the Robinson annulation product?:...
28. Which intermediate is not on the mechanistic pathway directly leading to the Robinson annulation product?:...
28. Which intermediate is not on the mechanistic pathway directly leading to the Robinson annulation product?: O ONa ONa & التملة ONa A. B. ONa OH C. D. 29. The Robinson annulation is best described as a(n): A. aldol followed by a conjugate addition B. Michael reaction followed by an aldol C. double aldol followed by an E1cb elimination D. alkylation, then aldol, then a Michael addition
28. Which intermediate is not on the mechanistic pathway directly leading to the Robinson annulation product?:...
28. Which intermediate is not on the mechanistic pathway directly leading to the Robinson annulation product?: ONa ONa & Go & ONa A. ONA OH D 29. The Robinson annulation is best described as a[n): A. aldol followed by a conjugale addition B. Michael reaction followed by an aldol C. double aldol followed by an E1cb elimination D. alkylation, then aldol, then a Michael addition
6) Predict missing starting compound and reagent in the following transformations (14 points). a. Robinson annulation...
6) Predict missing starting compound and reagent in the following transformations (14 points). a. Robinson annulation reaction: Michael addition followed by aldol condensation O- NaOEt EtOH aldol condensation product Michael addition product aldol addition product
The Robinson annulation is a classic example of what could be considered a paired reaction - that...
please complete number 1 and 2 COMPLETELY
The Robinson annulation is a classic example of what could be considered a paired reaction - that is a reaction that is made up of a sequence of two simpler reactions. In the case of the Robinson annulation, it is a Michael Addition followed by an intramolecular aldol. For the following Robinson annulation, go through the mechanism of the initial Michael addition and then look at how many different intramolecular aldol reactions could...
1. The Robinson annulation is a classic example of what could be considered a paired reaction-...
1. The Robinson annulation is a classic example of what could be considered a paired reaction- that is a reaction that is made up of a sequence of two simpler reactions. In the case of the Robinson annulation, it is a Michael Addition followed by an intramolecular aldol. For the following Robinson annulation, go through the mechanism of the initial Michael addition and then look at how many different intramolecular aldol reactions could happen. Analyze each one in terms of...
The following compound undergoes an intramolecular Robinson annulation reaction consisting of a conjugate addition followed by...
The following compound undergoes an intramolecular Robinson annulation reaction consisting of a conjugate addition followed by an aldol condensation. Draw the final product. No mechanism needed. Question 3 ( 5 points ) СН3 HO molargla H3C Create OscerSketch Answer 3 Question 4 Predict the product of the following reaction sequence. Draw the single main product structure only. ( 5 points ) H3C LDA (acid workup) Create OscerSketch Answer 4
1. A Robinson annulation is a reaction that involves: (i) a Michael addition of an enolate...
1. A Robinson annulation is a reaction that involves: (i) a Michael addition of an enolate onto an ,ß-unsaturated enone followed by (ii) an intramolecular aldol reaction. The molecule shown below (cyclohexenone X) can be made through two different Robinson annulation reactions. (A) Show the two different sets of starting materials (i.e. ketone 1 &a,p-unsaturated enone 1 and ketone 2 & a,B-unsaturated enone 2) for each Robinson annulation. Draw the reagents/reaction conditions. (B) Then pick one set and draw an...
can someone answer these 3 questions? 1. What will be the product of the following synthesis?...
can someone answer these 3 questions?
1. What will be the product of the following synthesis? 3. Robeson Annulation reaction has what type of mechanism? NaCN OH LICECH но HẠO, H. A. Aldol Condensation B. Dieckman Condensation C. Michael Addition followed by Aldol condensation D. Both A and B E. none of the above B c OH D SOH E None of the above 2. What will be the correct classification of the following compound? -ΝΗ A. Primary amine B....
For letters h & i : For each of the following reactions, predict the major mechanistic pathway (SN1/SN2/E1/E2...
For
letters h & i :
For each of the following reactions, predict the major
mechanistic pathway (SN1/SN2/E1/E2) and the major organic
products
1. (cont.) (h) НСОН CHB -CHBr HCOH - (0) CH,CH,CH,CH,Br- NH 2. For each of the following indicate which reaction will occur faster. Explain your reasoning. (No credit will be given for guesses) (a) The reaction of (CH),CBr with 0.001M aqueous NaOH or 0.10M aqueous NaOH (b) The reaction of 2-bromobutane with NaOH in DMSO or NaSH...
28. Which intermediate is not on the mechanistic pathway directly leading to the Robinson annulation product?: O ONa ONa & التملة ONa A. B. ONa OH C. D. 29. The Robinson annulation is best described as a(n): A. aldol followed by a conjugate addition B. Michael reaction followed by an aldol C. double aldol followed by an E1cb elimination D. alkylation, then aldol, then a Michael addition
28. Which intermediate is not on the mechanistic pathway directly leading to the Robinson annulation product?: ONa ONa & Go & ONa A. ONA OH D 29. The Robinson annulation is best described as a[n): A. aldol followed by a conjugale addition B. Michael reaction followed by an aldol C. double aldol followed by an E1cb elimination D. alkylation, then aldol, then a Michael addition
6) Predict missing starting compound and reagent in the following transformations (14 points). a. Robinson annulation reaction: Michael addition followed by aldol condensation O- NaOEt EtOH aldol condensation product Michael addition product aldol addition product
please complete number 1 and 2 COMPLETELY
The Robinson annulation is a classic example of what could be considered a paired reaction - that is a reaction that is made up of a sequence of two simpler reactions. In the case of the Robinson annulation, it is a Michael Addition followed by an intramolecular aldol. For the following Robinson annulation, go through the mechanism of the initial Michael addition and then look at how many different intramolecular aldol reactions could...
1. The Robinson annulation is a classic example of what could be considered a paired reaction- that is a reaction that is made up of a sequence of two simpler reactions. In the case of the Robinson annulation, it is a Michael Addition followed by an intramolecular aldol. For the following Robinson annulation, go through the mechanism of the initial Michael addition and then look at how many different intramolecular aldol reactions could happen. Analyze each one in terms of...
The following compound undergoes an intramolecular Robinson annulation reaction consisting of a conjugate addition followed by an aldol condensation. Draw the final product. No mechanism needed. Question 3 ( 5 points ) СН3 HO molargla H3C Create OscerSketch Answer 3 Question 4 Predict the product of the following reaction sequence. Draw the single main product structure only. ( 5 points ) H3C LDA (acid workup) Create OscerSketch Answer 4
1. A Robinson annulation is a reaction that involves: (i) a Michael addition of an enolate onto an ,ß-unsaturated enone followed by (ii) an intramolecular aldol reaction. The molecule shown below (cyclohexenone X) can be made through two different Robinson annulation reactions. (A) Show the two different sets of starting materials (i.e. ketone 1 &a,p-unsaturated enone 1 and ketone 2 & a,B-unsaturated enone 2) for each Robinson annulation. Draw the reagents/reaction conditions. (B) Then pick one set and draw an...
can someone answer these 3 questions?
1. What will be the product of the following synthesis? 3. Robeson Annulation reaction has what type of mechanism? NaCN OH LICECH но HẠO, H. A. Aldol Condensation B. Dieckman Condensation C. Michael Addition followed by Aldol condensation D. Both A and B E. none of the above B c OH D SOH E None of the above 2. What will be the correct classification of the following compound? -ΝΗ A. Primary amine B....
For
letters h & i :
For each of the following reactions, predict the major
mechanistic pathway (SN1/SN2/E1/E2) and the major organic
products
1. (cont.) (h) НСОН CHB -CHBr HCOH - (0) CH,CH,CH,CH,Br- NH 2. For each of the following indicate which reaction will occur faster. Explain your reasoning. (No credit will be given for guesses) (a) The reaction of (CH),CBr with 0.001M aqueous NaOH or 0.10M aqueous NaOH (b) The reaction of 2-bromobutane with NaOH in DMSO or NaSH...
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