A cell is found to have a high degree of methylation on the promoter for the...
Sorry for bad grammar, English is not my native language.
For question 11 what is a haploid yeast cell? If the cell lacks
the promoter in the first then will it always be true
that expression will not occur despite the UAS sequence?
What is a UAS sequence?
For question number 13 response b how/why when a promoter is
closer to a consensus sequence more transcription occurs?
11. Galactose dependent transcription is regulated by the Gal4 transcription factor which binds...
Normally the FMR1 locus does not have DNA methylation in the gene or promoter region. However, copies of the FMR1 gene with mutation length CGG repeats are modified; they have DNA methylation extending into the promoter region. This leads to ____________ expression of that copy of the FMR1 gene. no change in decreased increased
What would happen to the expression of this gene if this cell
did not have any GAL4 protein and why?
What would happen to the expression of this gene if this cell
did not have any GAL80 protein and why?
What would happen to the expression of this gene if this cell
did not have any GAL3 protein and why?
Understanding regulation of transcription in eukaryotes. The images below depict how the expression of a gene required to break down...
In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3 UTR of the mRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a histone acetyl transferase (HAT) which is an enzyme that acetylates histones when the protein is in its active form In a lung cancer cell line, the p101 protein is overly active leading to misregulation of gene...
Question: In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3’UTR of the mRNA transcript encoded by the ABC gene. The ABC gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a histone acetyl transferase (HAT) which is an enzyme that acetylates histones when the protein is in its active form. A. In a lung cancer cell line, the p101 protein is overly active leading to misregulation of...
Could you please provide the best answer for following MCQs. Thank you. Question 1 The imprinting control region is best defined as a promoter that regulates the expression of MeCP2 a sequence that can be methylated or unmethylated to control the expression of one or more genes by regulating promoter-enhancer interactions a sequence that when unmethylated can bind RNA polymerase II to induce promoter activation an enhancer that is inhibited when methylated Question 2 Imprinting is best described as a...
Question 1 Match the term with the best definition or description; most topics relate to the regulation of gene expression. General type of protein which will increase transcription rates when it attaches to a site A. Factor connected to a particular gene - B. Co-repressor C. Enhancer D. Promoter E. Structural F. Intron G. Activator H. Operator I. Basal transcription J. Glucocorticoid receptor K. Sigma factor L. Mediator M. Inducer N. TATA box O. Repressor The rates of mRNA produced...
Scientists have engineered bacteria to produce human proteins such as human growth hormone (hGH) to help treat dwarfism. Suppose the unmodified eukaryotic gene coding for hGH is inserted directly into a bacterial chromosome. Select the reasons why no expression would be seen in the bacterial cell for the hGH gene. Bacteria cannot remove intronic sequence from a gene, so if the gene for hGH were transcribed, it would translate to a nonfunctional protein. The bacterial nucleoid does not have the...
Questions 8-9: In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3'UTR of the MRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a DNA methyltransferase (DNMT) which is an enzyme that methylates DNA when the protein is in its active form. 8. 8. (1pt) In a lung cancer cell line, the p101 protein is overly active leading to...
Genetics Worksheet Week 3: Gene Regulation and Epigenetics 1. Duchenne muscular dystrophy is caused by a mutation in a gene that is 2.5 million nucleotides in length and encodes a protein called dystrophin. The dystrophin protein itself is 3684 amino acids in length. Calculate below the approximate size of the mRNA that encodes dystrophin. Approximately what percentage of the gene that encodes dystrophin is intron sequence? The human genome encodes a much greater variety and number of proteins than the...