Question

Which of the following functions of glutamyl-prolyl tRNA synthetase is a noncanonical function? Group of answer...

Which of the following functions of glutamyl-prolyl tRNA synthetase is a noncanonical function?

Group of answer choices:

A. catalyze aminoacylation of glutamic acid tRNA

B. catalyze aminoacylation of proline RNA

C. phosphorylation and activation of the kinase S6K1

D. interact with fatty acid transport protein 1 and increase lipid uptake

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Answer #1

Answer- A. catalyze aminoacylation of glutamic acid tRNA.

Reason- Aminoacyl tRNA synthetases (ARS) catalyzes the ligation of amino acids to cognate tRNAs. The glutamyl-prolyl-tRNA synthetase (GluProRS) is a bifunctional ARS. It has non-canonical activity that blocks synthesis of a specific protein.

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