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A) what effect does increasing a cell's NADH/NAD+ ratio have? 1. No effect on citric acid...

A) what effect does increasing a cell's NADH/NAD+ ratio have?

1. No effect on citric acid cycle activity

2. decrease in citric acid cycle efficiency

3. decrease in citric acid cycle activity

4. increase in citric acid cycle activity

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Answer #1

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NADH/NAD+ ratio is increased in the cell. It means NADH concentration is higher than NAD+ in the cell.

Citric acid cycle occurs in the mitochondrial matrix. In this cycle, NAD+ is converted into NADH. That's why NAD+ concentration should be higher in the cell for increasing the rate of citric acid cycle.

But there are found lower concentration of NAD+ in the cell as compared to NADH. That's why there are found decrease in rate of citric acid cycle. Hence citric acid cycle activity is decreased in this case.

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Answer is:3. decrease in citric acid cycle activity

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