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Question 22 1 pts How do naïve and mature lymphocytes differ? Mature lymphocytes cannot bind to antigens Naive lymphocytes ca
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Option - Naive Lymphocytes have not encountered an antigen before is the correct answer. As naive lymphocytes are those that have not come in contact with the antigen they circulate in the blood, lymphatic vessels, and tissues freely. Naive cells only get activated when they receive signals from antigen-presenting cells. After that, they differentiate either into the B or T cells.

However, the mature Lymphocytes are those that can fight against infections. It consists of B- cells or T- cells. They help to fight against the infection by activating the immune system. So the option that mature lymphocytes cannot bind to the antigen is incorrect as they can proliferate and help in getting rid of the infection successfully. The other option mature lymphocytes have not encountered an antigen is incorrect as they contain antigen-presenting cells that help them to binds to the antigen and generate an adequate response to right the infection and if the infection is reoccurring they have memory cells that help in fight back. Naive cells only get activated when they receive signals from antigen-presenting cells. After that, they differentiate either into the B or T cells and the same is the case with the mature Lymphocytes they can switch back likewise the B Lymphocytes can differentiate into B specialized cells or T- cells. So it is also incorrect.

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