Question

Question 13 3 pt: MHC I and MHC Il differ from each other in that: MHC I, but not MHC II, is necessary for T cells to kill cells presenting endogenous antigen MHC I, but not MHC II, primarily present exogenous antigens to CD8+ T cells MHC I, but not MHC II, is necessary for T cells to activate B cells MHC II, but not MHC I, primarily present endogenous antigens to CD4+ T cells Question 14 3 pts In an inherited form of "bare lymphocyte syndrome," cells fail to make MHC II molecules. Which of the following would result from this condition? Naive B cells cannot develop Naive CD8+ T cells will not form Endogeneous antigenic peptides cannot bind MHC molecules in the endoplasmic reticulum Effector CD4+ T cells will not be present

Answer 1

13. Except for option C (MHC 1, but not MHC 2, is necessary for T cells to activate B cell ), all other options are correct.
In the case of T cell-dependent B cell activation, the B cell is activated by the activation of helper T cells. Helper T cells become activated when they are presented with peptide antigens by MHC class II molecules.
14 Effector CD4+ T cells will not be present
CD4+ T cells, also known as Helper T cells, become activated when presented with peptide antigens by MHC class II molecules. B cells can develop through T cell-independent pathways.