Question

Another exaumple of haptens body to Per response occurs wi The best known example of Handout IG2-1 Categorization Categorize the characteristics in the following list with the appropr complex (MHC) class Expressed on all nucleated cells .Peptide-binding cleft is closed at both ends Presents endogenous antigen to CD8+ T cells . Has one alpha chain and beta:-microglobulin . Peptide-binding site holds peptides between 8 and 11 amimacrophages cells, and thymic epithelium) ting cells (B lymphocytes, monocytes, macrophages, dendritic . Has an alpha chain and a beta chain Peptide-binding site holds peptides between 13 to 18 amino acid Presents exogenous antigen to CD4 T cells Peptide-binding cleft is open at both ends CLASS I MHC MOLECULE CLASS II MHC MOLECULE

Answer 1

ANSWER

*Categorization of characterstics of class I MHC and class II MHC.

CLASS I MHC MOLECULE	CLASS II MHC MOLECULE.
* Expressed on all nucleated cells.	* Expressed on antigen presenting cells (B lymphocytes,monocytes,macrophages,dentritic cells and thymic epitheliem).
* Peptide binding cleft is closed at both ends.	* Peptide binding cleft is open at both ends.
* Peptide binding site holds peptides between 8 to 11amino acids long.	* Peptide binding site holds peptides between 13 to 25    amino acids long.
* Present endogenous antigen to CD8 + T cells.	* Present endogenous antigen to CD4 + T cells.
* Has one alpha chain and beta-2 microglobulin.	* Has an alpha chain and a beta chain.