3. (4 pts) Puromycin is an antibiotic that has an effect on both prokaryotes and eukaryotes....
3. (4 pts) Puromycin is an antibiotic that has an effect on both prokaryotes and eukaryotes. The drug, which is structurally similar to the aminoacyl terminus of an aminoacyl-tRNA (see figure below), inhibits protein synthesis by releasing nascent polypeptide chains before their synthesis is completed. н,с CH NH2 N N N CH CH HC нс. N N O 'N HOCH 0 R-O-POCHO H H 0 H H H H H H HAN OH O OH CO C=0 H-C-CH2 OCH H-C-R NH NH2 Puromycin Aminoacyl-tRNA Explain how puromycin can have this effect on growing polypeptide chains during translation (specifically, where does it reside within the ribosome) and why the peptide chains would be prematurely released.