Question

14. A 19. vial of Clafocan has no instructions for reconstitution on the label, but comes with the insert printed below Preparation: Claforan for IM or IV administration should be reconstituted as follows: Strength Amount of Diluent (ml) Concentration (mg/mL) IM 500 mg vial 2 230 1 g vial 3 300 2 g vial 5 330 TV 500 mg vial 10 50 1 vial 10 95 2 g vial 10 180 For an order of 0.45 g Clafocan, IM, (a) how much diluent should you add? and (b) how much should you give?

Answer 1

14 (Desered) 4 50 mg 0.45gm: Dose required aftee reconstitution 500 ng used vial should be Total concentration have it will 230 ng/me . 460 mg/2ml. (have) Available dose 460 ng la me Desired dose x Volunae have Desired volume = Dose have 450 X 2 = 1.956 me 460 diluent 2 me ) a) IM soo ng vial b) 1.96 me 3) q8h dose = 300 mg BEC Patent dose = as to so patient weight = 50 16= 22.68 kg Recomended mg / kg (3 doses) day) (25 to So) 22.66 kg 567- 1134 mg / day (sdares/ bu) patient weight fol 300 X 3 Total goong recomended dose pue day is 567-1134 mg 1 day alachanned with their stanguer

dose safe. The 300 mg Dose desired (Have) Available 250 mg / 1.8 me derse Desired x Volume have Desired volume = Dose have 300 x 1.8 2.16 me 2 SO 28h 2,16 me having 300 ng should be given 160 mg Required dire = 0.16 og = Cefadyl seluted 15 loq me diluent Gore and 1.9 me ot has cone lime 100 ng have 1.9 x 100 = 190 mg. (have) Available 190 mg / 1.9 me Desined dose = 160 mg Destred dose x Volume have Desired volume = Dose have 160 X1.9 1.6 me 190 * The diluent selated 1.9 me because it sufficient generate the lowest & Volume and low waste as CS Scanned with CamScanner de constituted solution be Used with in should

hows it 48 else ou will be degraded. shalced with vremove © Initially the vial powdee as to min powdee throughly to diluent add bulking and now the vial recomended until the to half of Capacity and shake powde dissolve completely. Now add remaining diluent upto prescribed mark it is ready to administee. the and shake Desired dose 700,000 units which will have selected 3ml IS Diluent units slme 1,000,000 Destured dose x Volnue have Desired volume = Dose have 7,00,000 077 ml 1 000 000 7,00,000 1,000,000 selected be cane it diluent generate * 3 m out lowest waste of drug lowest volume which generate high dose compared to other be used csatarbrood wit blonnenscanner 48 ha.