Question

Human papillomavirus (HPV) is a virus that can cause cancer of the cervix, vagina, penis, pharynx, and anus.

Once in human cells, the HPV will produce a protein called E7 that acts as an oncogene by inactivating Rb.

Based on this information, the protein E2F would most likely be found in which part of the cell, if the cell was infected with HPV?

		Attached to Rb in the cytoplasm.
		Not attached to Rb and in the cytoplasm.
		Outside of the cell since it will be exported.
		Not attached to Rb and in the nucleus bound to specific promoters.

Answer 1

Ans Not attached to Rb and in the nucleus bound to Specific bromoteru 07 obtion d is correct choice Explaination PRb lios viesponsible for inhibiting cell cycle Stage boo gresion 9t stop activation of a s cyclin which is Responsible for Progression gt in active form cremain bound to Epf which is a trans oub tional factor . But PRb is inactivated it releases Caf move to nucleus bind to specific Transuribe gene for cyclin cell cycle progress. as soon as Promotersregión So d correct. CS Scanned with CamScanner