Which of the following molecules would you expect to have the highest pka? Note that the...
Which of the following molecules would you expect to have the highest pka? Note that the most acidic hydrogen in each molecule has been drawn in red. ОН Br ОН F ОН CI ОН
Rank the following structures from highest acidity (lowest pKa value) to lowest acidity (highest pKa value). The acidic hydrogen is indicated in red in each structure. Rank the following structures from highest acidity (lowest pKa value) to lowest acidity (highest pKa value). The acidic hydrogen is indicated in red in each structure.
Organic Chemistry 4. Below are two molecules, B and C. Explain the differences in pKa of the two molecules by drawing the conjugate base of molecule C and a resonance structure that would not be found in molecule B. Hint: Draw out the NO2 group. conjugate base of molecule C pKa- 29.5 molecule B NO2 pka= 8.6 molecule C 5. Below is the molecule Abilify, which is a top selling drug that is used to treat schizophrenia, bipolar disorder and...
of the five labeled protons in this molecule, which do you expect would have the highest and the lowest chemical shift? Question 8 Of the five labeled protons in this molecule, which do you expect would have the highest and the lowest chemical shift (8)? U III H Η Η Η C C-C-CH3 H F H I highest; IV lowest V highest; I lowest V highest; IV lowest I highest; V lowest II highest; III lowest Oll highest; IV lowest...
1-5 Problem I: Give the approximate pka of the indicated H's in the following molecules: Problem II: Circle the most acidic proton in the following molecules: Problem IV: Using ARIO order the following molecule in decreasing order: Problem V: Indicate the direction the reaction would go by placing the appropriate arrows: (reaction goes from lowest to highest pka) + OH + H2O
How many signals would you expect each of the following molecules to have in its 'H and 1C spectra? Molecule #1 Molecule #3 Molecule #2 НэС CHз CH3CH2C(CH3)2CH2CH3 H-NMR absorptions absorptions absorptions 3C-NMR absorptions 13 | absorptions absorptions How many signals would you expect each of the following molecules to have in its 'H and 1C spectra? Molecule #1 Molecule #3 Molecule #2 НэС CHз CH3CH2C(CH3)2CH2CH3 H-NMR absorptions absorptions absorptions 3C-NMR absorptions 13 | absorptions absorptions
10. Consider the following alkyl chlorides. Which would you expect to undergo an SN1 substitution most readily? Justify your answer CI CI 11. Which of the following would you expect to be most acidic? Justify your answer Which of the following would you expect to be the stronger base? Justify your answer 12.
Of following reactions, which one(s) would you expect to have a negative AS? Br + Br2 Br OH CI + HCI IV Br
Interactive Case Study # 2 Henderson Hasselbach Relationship Can you help me find the correct pKa for each compound, and explain which one is the right answer? (d) Gaba, an important neurotransmitter in the human brain, is represented in different ionization states below. Circle the most dominant form of this compound at pH-7. Show work to justify how you arrived at this answer. To help, a generic pKa table has been provided on the next page but these values can...
QUESTION 18 Which of the following types of companies would you expect to have the highest inventory turnover ratio? A law firm A construction company A fine jewelry retailer A grocery store