Question

What do the results in Table 22.4 suggest about sickle-cell hemoglobin and malaria? A hemoglobin genotype in children normal (homozygous normal) mild sickling (heterozygous) B hemoglobin genotype in adult males normal (homozygous normal) mild sickling (heterozygous) percent with malaria parasite present 45.7 27.9 percent with malaria parasite present 93.3 13.3 percent with high parasite density 66.0 33.3 percent with high parasite density 40.0 0 Table 22.4. Incidence of the malaria parasite in blood of normal and sickle-cell children from a small community in Uganda, Africa, and adult males dosed with the malaria parasite. Normal individuals have a selective advantage in regions where malaria is not present. Homozygous individuals with sickle-cell disease died before the results were in. Heterozygous individuals have a selective advantage in regions where malaria is prevalent. Heterozygous individuals tend to have much lower infection rates than normal homozygous individuals.

Answer 1

1)Options 1,3 and 4 are correct.

2nd one is not correct because,in the given table nothing is mentioned about homozygous for sickle cell disease.

2)Options 1,2,3 and 4 are correct.

2nd one is correct,because amount of antibodies produced in different routes is different.

4th one is also correct. Reinserting OSP-C gene proved neccessity of gene OSP-C in inducing antibodies production in mice.