Ans (c) : All of the choices
* Glycolysis : In glycolysis, glucose (a six-carbon sugar) undergoes a series of enzyme catalyzed reactions & gets converted into two molecules of pyruvate (three-carbon organic molecule) .Each pyruvate from glycolysis goes into the mitochondrial matrix & gets converted into acetyl CoA.
* Citric acid cycle / TCA cycle : The acetyl CoA made in the last step combines with a four-carbon molecule and goes through a cycle of reactions, ultimately regenerating the four-carbon starting molecule. The net result of citric acid cycle is that for each acetyl group entering the cycle as acetyl-CoA , two molecules of CO2 are produced.
Acetyl-CoA + 3NAD+ + FAD + GDP/ADP +3H2O -->
2CO2 + 3NADH + FADH2 + GTP/ATP + H2O
* Oxidative phosphorylation : Most of the free energy released during the oxidation of glucose to CO2 is retained in reduced coenzymes NADH & FADH2 , generated during glycolysis & TCA cycle. Electrons are released from NADH & FADH2 & eventually transferred to O2 , forming H2O, through electron transport chain.
As electrons move down the chain, energy is released and used to pump protons out of the matrix, forming a gradient. Protons flow back into the matrix through an enzyme called ATP synthase, making ATP.
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