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Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 OTs reagent(s) OH TsCl, Et N sOj, HCI 0 SO, TsOH, CH3OH
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Answer #1

The most appropriate reagent will be option A TsCl, Et3N. Treatment of alcohol with tosyl chloride (TsCl) in presence of base will produce the given sulfonate ester. A base is required for this reaction and triethyl amine is the base here which is supplied to neutralize the produced HCl as side product. This is a substitution reaction where O-H bond substituted by O-S bond and Et3N will speed up the forward reaction by HCl neutralization.

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Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 OTs reagent(s) OH...
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