Choose the most appropriate reagent(s) for the conversion of (R)-3-bromo-2-methylpentane to (S)-3- azido-2-methylpentane. TsCI pyridine HOH...

Question

Question

Choose the most appropriate reagent(s) for the conversion of (R)-3-bromo-2-methylpentane to (S)-3- azido-2-methylpentane. TsC

science chemistry

Add a comment Improve this question Transcribed image text

Answer 1

Answer #1

OPTION A

NaN3 has more N3- ion concentration [than weak acid HN3] and N3- ion is a strong nucleophile. In presence of polar aprotic solvent like dimethylsulfoxide , the reaction proceeds by SN2 giving the desired product.

Using NaNH2 or NH2NH2 or NH3 would not result in formation of azide ion required.

Add a comment

Answer 2

Similar Homework Help Questions

Choose the most appropriate reagent(s) for the conversion of propyne and 2-methyl-1-tosyloxypropane to 5-methyl-2-hexyne. 1. reagent(s)...

Choose the most appropriate reagent(s) for the conversion of propyne and 2-methyl-1-tosyloxypropane to 5-methyl-2-hexyne. 1. reagent(s) :a 2. OTS TSCI, Et3N он NaNH2, NH3 3NaOH, H20 H2SO4 KOCH2CH3, HOCH2CH3 NH3
Choose the most appropriate reagent(s) for the conversion of the amide to the amine target molecule....

Choose the most appropriate reagent(s) for the conversion of the amide to the amine target molecule. SOCI2 Ph OH Ph CI HN Ph N reagent(s) I- I- A H2, Pd B NaBH4, CH3OH © NaNH2, NHz 1. LiAIH4 2. H*, H20 E NH2NH2, KOH
Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 OTs reagent(s) OH...

Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 OTs reagent(s) OH TsCl, Et N sOj, HCI 0 SO, TsOH, CH3OH

what would be the reagent? Part 7 out of 8 Choose the most appropriate reagent(s) for...

what would be the reagent? Part 7 out of 8 Choose the most appropriate reagent(s) for the conversion of the cis-epoxide intermediate to the target molecule. H2, Lindar catalyst CH3CO3H OH reagent(s) HOH A H,O, H,SO H,O, HBO CH,0 D 1.03 2. CH_SCH @ H20, HCI 2 attempts left 2 atempts et Check my work Next part
Choose the most appropriate reagent(s) for conversion of ethylene to ethyl bromide. H H reagent(s) >...

Choose the most appropriate reagent(s) for conversion of ethylene to ethyl bromide. H H reagent(s) > CH3CHBr - CH3CH2MgBr 0.5 points eBook Print References В HOBr C Br2, H20 D NaBr, H20 E HBr
Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 -CH3 reagent(s) I...

Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 -CH3 reagent(s) I A 101, Et @ 1,80, H20 C SO3, HCI OSO E TSOH, CH,OH Next part

Name the following compound below with correct stereochemistry. CH Br r -H H-CH, CH,CH, (25,3S)-2-bromo-3-methylpentane (20,35)-2-bromo-3-methylpentane...

Name the following compound below with correct stereochemistry. CH Br r -H H-CH, CH,CH, (25,3S)-2-bromo-3-methylpentane (20,35)-2-bromo-3-methylpentane (25,3R)-2-bromo-3-methylpentane (2R 3R)-2-bromo-3-methylpentane
Choose the most appropriate reagent(s) for the conversion of benzyl alcohol to benzaldehyde. OH H reagent(s)...

Choose the most appropriate reagent(s) for the conversion of benzyl alcohol to benzaldehyde. OH H reagent(s) H OH H CI
Choose the most appropriate reagent(s) for conversion of methyl bromide to methylmagnesium bromide. он reagent(s) 3Mg(OCH3)2,...

Choose the most appropriate reagent(s) for conversion of methyl bromide to methylmagnesium bromide. он reagent(s) 3Mg(OCH3)2, diethyl ether C Mg dicthyl ether O MgS04, H20 MgBr2, diethyl ether

E: 1.NaNH2, 2.CH3CH3 Choose the most appropriate reagent(s) for the first step of the synthesis. reagent(s) HH = H А) 1....

E: 1.NaNH2, 2.CH3CH3 Choose the most appropriate reagent(s) for the first step of the synthesis. reagent(s) HH = H А) 1. NaNH, 2. CH3CH2OH 6 CH3CH2OH C CH3CHBI 1. NaNH2 2. CH3CH2Br 1. NaNH,

Choose the most appropriate reagent(s) for the conversion of (R)-3-bromo-2-methylpentane to (S)-3- azido-2-methylpentane. TsCI pyridine HOH...

Homework Answers

Add Answer to:
Choose the most appropriate reagent(s) for the conversion of (R)-3-bromo-2-methylpentane to (S)-3- azido-2-methylpentane. TsCI pyridine HOH...

Post as a guest

Earn Coins

Choose the most appropriate reagent(s) for the conversion of propyne and 2-methyl-1-tosyloxypropane to 5-methyl-2-hexyne. 1. reagent(s)...

Choose the most appropriate reagent(s) for the conversion of the amide to the amine target molecule....

Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 OTs reagent(s) OH...

what would be the reagent? Part 7 out of 8 Choose the most appropriate reagent(s) for...

Choose the most appropriate reagent(s) for conversion of ethylene to ethyl bromide. H H reagent(s) >...

Choose the most appropriate reagent(s) for the conversion of 2-methyl-1-propanol to 2-methyl-1-tosyloxypropane. CH3 -CH3 reagent(s) I...

Name the following compound below with correct stereochemistry. CH Br r -H H-CH, CH,CH, (25,3S)-2-bromo-3-methylpentane (20,35)-2-bromo-3-methylpentane...

Choose the most appropriate reagent(s) for the conversion of benzyl alcohol to benzaldehyde. OH H reagent(s)...

Choose the most appropriate reagent(s) for conversion of methyl bromide to methylmagnesium bromide. он reagent(s) 3Mg(OCH3)2,...

E: 1.NaNH2, 2.CH3CH3 Choose the most appropriate reagent(s) for the first step of the synthesis. reagent(s) HH = H А) 1....

Choose the most appropriate reagent(s) for the conversion of (R)-3-bromo-2-methylpentane to (S)-3- azido-2-methylpentane. TsCI pyridine HOH...

Homework Answers

Add Answer to: Choose the most appropriate reagent(s) for the conversion of (R)-3-bromo-2-methylpentane to (S)-3- azido-2-methylpentane. TsCI pyridine HOH...

Post as a guest

Earn Coins

Add Answer to:
Choose the most appropriate reagent(s) for the conversion of (R)-3-bromo-2-methylpentane to (S)-3- azido-2-methylpentane. TsCI pyridine HOH...