Question

Which is the most inappropriate description of enzyme inhibition?

Select one:

a. A competitive inhibitor increases Km only.

b. A noncompetitive inhibitor decreases Vmax only.

c. An uncompetitive inhibitor decreases both Km and Vmax.

d. All of the above

e. None of the above

Answer 1

THE ANSWER IS OPTION E

REASON

1. Competitive inhibitors only bind with E. So they increase the Km with the interfering with the binding of substrate and they don't interfere in the catalysis so they don't affect the Vmax. So option 1 is correct

2. In non compititive inhibition as we change the amount of inactive enzyme the V max will change. So the Vmax will decrease in the presence of a non competitive inhibitor. So the 2nd option is true

3.un competitive inhibitors binds with ES COMPLEX. Because of the high binding efficiency they decrease the Km and because of interfering substrate binding and hamper catalysis in ES COMPLEX Vmax also decreases. So the 3rd option is also true