Cotranslational translocation requires these two E.R. proteins: Translocon and the SRP receptor SRP receptor and BIP...
Cotranslational translocation requires these two E.R. proteins:
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Translocon and the SRP receptor |
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SRP receptor and BIP |
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Sec63 complex and the SRP receptor |
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Sec63 complex and BIP |
Homework Answers
Translocon and the SRP receptor
Some of the secretory proteins such as those reside in endoplasmic reticulum uses cotranslational translocation pathway. Translocon and SRP (signal recognistion particle) receptor proteins are essential for this pathway.
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Cotranslational translocation requires these two E.R.
proteins:
Translocon and the SRP receptor
SRP receptor and BIP...
Translocation of most proteins into the ER requires all of the following EXCEPT a(n): Select one:...
Translocation of most proteins into the ER requires all of the following EXCEPT a(n): Select one: a. Importin receptor b. Ribosome c. Signal sequence d. Translocon/Sec61 complex e. Signal Recognition Particle
1. (14pts) A. What are the functions of the signal recognition particle (SRP) and translocon in p...
PLEASE ANSWER ALL THE QUESTIONS IN EACH PART. THANK YOU!
1. (14pts) A. What are the functions of the signal recognition particle (SRP) and translocon in protein transport to the ER? SRP Translocon B. How does the translocon determine which orientation to insert membrane proteins? C. How do budding & fusion affect the orientation of integral membrane proteins during vesicle transport? D. Consider a ligand-gated ion channel at the plasma membrane that binds to ligands in the cytoplasm. From a...
Using the hydropathy profile shown below (Y axis: hydropathy), researchers identified two significant stretches of hydrophobic...
Using the hydropathy profile shown below (Y axis: hydropathy), researchers identified two significant stretches of hydrophobic aminoacid residues (highlighted in red). Name each one of them and explain their significance for the localization of this protein. (a) Human growth hormone receptor (type 1) N-terminus 200 400 500 C-terminus 1. Where do you expect the mRNA coding for human growth hormone receptor to be translated? 2. Which part of this protein will be recognized by the signal recognition particle (SRP)? 3....
Drag the terms on the left to the appropriate blanks on the right to complete the...
Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Terms can be used once, more than once, or not at all. Reset Help transport vesicle(s) Soon after initiation of translation of an mRNA coding for a secretory protein, the of the secretory protein is synthesized and is exposed on the surface of the ribosome. The signal recognition particle (SRP) contains the that marks this protein for into the endoplasmic reticulum cotranslational translocation...
Protein trafficking has been one of the biggest challenges to explore and elucidate in the past...
Protein trafficking has been one of the biggest challenges to explore and elucidate in the past few decades. Yet we now know much about this multi-step process. d. Explain how proteases were used with rough microsomes to demonstrate the presumed presence of an SRP receptor. e. Explain the differences between co-translational translocation versus post-translational translocation of newly synthesized proteins. What is the role of Bip in the latter process? f. Challenge: You are studying a particular protein (Protein Z) that...
The import of proteins into mitochondria requires energy in the form of ATP for their [____]...
The import of proteins into mitochondria requires energy in the form of ATP for their [____] and of mitochondria that are energized, with an electrochemical gradient. The imported proteins must be synthesized on [____] ribosomes as they are bound to requisite [____]. Protein import itself requires that the protein have an N-terminal targeting sequence that folds into an [____] for interaction with the import receptor on the outer mitochondrial membrane. The translocase of the outer membrane (TOM) complex consists of...
Splicing of nuclear pre-mRNAs requires a large complex of proteins and RNAs called the spliceosome. Discuss...
Splicing of nuclear pre-mRNAs requires a large complex of proteins and RNAs called the spliceosome. Discuss the functions of the spliceosome, the proteins and RNAs involved, and the dynamic nature of the spliceosome
B cell activation requires (select ALL that apply): O T cytotoxic cells O Tcell receptor (TCR)...
B cell activation requires (select ALL that apply): O T cytotoxic cells O Tcell receptor (TCR) binding to antigen displayed in MHC-|| O antigen binding to antibody on B cell surface T cell receptor (TCR) binding to antigen displayed in MHC-I Question 3 1 pts Which statement(s) about C proteins in the complement system is true (select ALL that apply): Cproteins are always active as they circulate through the body All of the C proteins are equally important for all...
Which of the following statements describing the import of proteins into the nucleus is correct? Answers...
Which of the following statements describing the import of proteins into the nucleus is correct? Answers A-D A Transport into the nucleus requires the activity of a G protein. B The receptor for nuclear proteins is found in the cytosol and travels into the nucleus with the protein being transported o С Proteins destined for the nucleus are transported in a fully-folded conformation. D These statements are all correct. o You are interested in a water-soluble protein that functions within...
Which method requires the experimental construction of two fusion proteins to assess protein–protein interactions? yeast two-hybrid...
Which method requires the experimental construction of two fusion proteins to assess protein–protein interactions? yeast two-hybrid system Western blot Northern blot immunoprecipitation
Translocation of most proteins into the ER requires all of the following EXCEPT a(n): Select one: a. Importin receptor b. Ribosome c. Signal sequence d. Translocon/Sec61 complex e. Signal Recognition Particle
PLEASE ANSWER ALL THE QUESTIONS IN EACH PART. THANK YOU!
1. (14pts) A. What are the functions of the signal recognition particle (SRP) and translocon in protein transport to the ER? SRP Translocon B. How does the translocon determine which orientation to insert membrane proteins? C. How do budding & fusion affect the orientation of integral membrane proteins during vesicle transport? D. Consider a ligand-gated ion channel at the plasma membrane that binds to ligands in the cytoplasm. From a...
Using the hydropathy profile shown below (Y axis: hydropathy), researchers identified two significant stretches of hydrophobic aminoacid residues (highlighted in red). Name each one of them and explain their significance for the localization of this protein. (a) Human growth hormone receptor (type 1) N-terminus 200 400 500 C-terminus 1. Where do you expect the mRNA coding for human growth hormone receptor to be translated? 2. Which part of this protein will be recognized by the signal recognition particle (SRP)? 3....
Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Terms can be used once, more than once, or not at all. Reset Help transport vesicle(s) Soon after initiation of translation of an mRNA coding for a secretory protein, the of the secretory protein is synthesized and is exposed on the surface of the ribosome. The signal recognition particle (SRP) contains the that marks this protein for into the endoplasmic reticulum cotranslational translocation...
B cell activation requires (select ALL that apply): O T cytotoxic cells O Tcell receptor (TCR) binding to antigen displayed in MHC-|| O antigen binding to antibody on B cell surface T cell receptor (TCR) binding to antigen displayed in MHC-I Question 3 1 pts Which statement(s) about C proteins in the complement system is true (select ALL that apply): Cproteins are always active as they circulate through the body All of the C proteins are equally important for all...
Which of the following statements describing the import of proteins into the nucleus is correct? Answers A-D A Transport into the nucleus requires the activity of a G protein. B The receptor for nuclear proteins is found in the cytosol and travels into the nucleus with the protein being transported o С Proteins destined for the nucleus are transported in a fully-folded conformation. D These statements are all correct. o You are interested in a water-soluble protein that functions within...
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