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a. Which one of the nitrogen waste products (ammonia/NH3 or ammonium/ NH4+) will be most likely...

a. Which one of the nitrogen waste products (ammon

a. Which one of the nitrogen waste products (ammonia/NH3 or ammonium/ NH4+) will be most likely to enter the portal blood from the colonic lumes? Please explain your answer.

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Answer #1

Physiological pH = 7.365 which is a basic pH.

At basic pH molecules will be prodeominantly in it's basic state, in this case NH3. Nevertheless, pKa = 9.3, and pH is 2 points below pka, the predominating species is the acidic form, NH4+

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