Explain what problems are associated with the following reaction
in each case.Homework Answers
The deisred product can not be formed in both cases .
reaction 1.
Bromide is a weaker nucleophile and base than hydroxide ion. Thus nucelophilic substitution cannot takeplace.
Secondly , -OH being a strong base, is a poor leaving group , making the substrate also less reactive. Thus NO Reaction takes place.
Reaction2.
Though using a strong base like ethoxide io , we expect elimination to take place, a different reactionoccurs here.
In the substrate along with Br(a primary alkyl halide) we have a keto group also, which is more electrophilic than the carbon attached to the bromide.
Thus the nucelophile/base ethoxide ion attacks preferably the carbonyl carbon rather than the carbo n with halogen. Thus acyl nucleophhilic attack is done rather than elimination.
Secondly a primary halide is less reactive towards elimination.
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Explain what problems are associated with the following reaction
in each case.
NaBr OH Br CH3...
09 Which is the major product of the following substitution reaction? CH₂CH₂OH NaBr ? A) CH₃...
09 Which is the major product of the following substitution reaction? CH₂CH₂OH NaBr ? A) CH₃ CH₂ Br D) All of the Above B) CH₃ CH₂ Na E) None of the Above c) CH₂-E-H 20 Which is the major product of the following sultitution reaction? CH₃ CH-CH-CH2 HBr ? OH CH₂ C) CH C=CH-CH₂ A) CH₂ CH-CH=CH₂ Br CH3 Br B) CH₂ C-CH₂=CH₂ D) None of the Above 2 Which is the major product of the following reaction? CH3 PBra...
is the major product of the following substitution reaction! CH₂CH₂OH NaBr ? A) CH₃ CH₂ Br D) All of the Above B) C...
is the major product of the following substitution reaction! CH₂CH₂OH NaBr ? A) CH₃ CH₂ Br D) All of the Above B) CH₃ CH₂ Na E) None of the above c) CH3-C-H 20 Which is the major product of the following substitution reaction? ? CHICH-CH-CH2 HBr CH OH CH₂ C) CH₂ C=CH-CH₂ Shy A) CH₂ CH-CH=CH₂ D) None of the Above. B) CH₃ ¢-CH₂-CH₃ Br 2) Which is the major product of the following reaction? CH3 CH PBr3 ? CH₂...
1. How many moles of NaBr will be produced by the following reaction in each case?...
1. How many moles of NaBr will be produced by the following reaction in each case? Na(s) + Br2() →NaBr (s) a. 1 mol Na and 0 mol Br2 b. 2 mol Na and 1 mol Br2 c. 3 mol Na and 1 mol Br2
the following compound is 9 Which is the major product of the follow CHOCH, OH NaBr...
the following compound is
9 Which is the major product of the follow CHOCH, OH NaBr ? of the following substitution reaction? D) All of the Above E) None of the Above A) CH₃ CH₂ Br B) CH3CH(Na, c) CH₂-E-H 20 Which is the major product of 5 CHA CH=CH-CH2 HBr ? the following substitution reaction? major product of CHE OH SHA A) CH₂ CH-CH=CH3 CH2 () CH3 C=CH-CH2 B) CH3 C- CH₂ - CH3 D) None of the Above...
please explain Identify the product of the following reaction: Br Br ONa САНаО2 2 NaBr NaO...
please explain
Identify the product of the following reaction: Br Br ONa САНаО2 2 NaBr NaO Product: Edit
Question 19 What is the product of the following reaction? excess HBT Br OH OH Br...
Question 19 What is the product of the following reaction? excess HBT Br OH OH Br ОН ОН Br Br Moving to another question will save this response. A Moving to another question will save this response. Question 20 What is the product of the following reaction? NaBHA ОН ОН A Moving to another question will save this response. A Moving to another question will save this response. Question 22 What is the starting material for the following reaction? 1....
The following reaction is a single-step, bimolecular reaction: CH, Br+ NaOH → CH,OH + NaBr When...
The following reaction is a single-step, bimolecular reaction: CH, Br+ NaOH → CH,OH + NaBr When the concentrations of CH3Br and NaOH are both 0.200 M, the rate of the reaction is 0.0040 M/s. (a) What is the rate of the reaction if the concentration of CH3Br is doubled? Number MIS (b) What is the rate of the reaction if the concentration of NaOH is halved? Number M/s (c) What is the rate of the reaction if the concentrations of...
7 the following substitution reaction? Which is the major product of the follow CHOCHOH NaBr ?...
7 the following substitution reaction? Which is the major product of the follow CHOCHOH NaBr ? A) CH₂ CH₂ Br B) CH CH. Na c) CH₂-E-H D) All of the Above E) None of the Above of the following substitution reaction? CHE is the major product of the following substitut CH₂CH=CH-CH2 HBr ? CHz CÓ CH2=CH-CH3 OH A) CH₂CH=CH-CH3 B) CH3C-CH₂-CH3 D) None of the Above ? Which is the major product of the following reaction? PBra ? CHCH OH...
the weakest base: CH3 HO HS the fastest in an Syl reaction: (CE)_CACHOSCH (CH3CB (CH.) CHCH(Br)CH, (CH),C(Br)CH (CH...
the weakest base: CH3 HO HS the fastest in an Syl reaction: (CE)_CACHOSCH (CH3CB (CH.) CHCH(Br)CH, (CH),C(Br)CH (CH3)2CHCH Br 2. For each pair of reactions given below indicate which is faster and explain your reasoning. + CHỊ N + C CH3Cl + N CH3 + Ng CH₃N₂ + i CHg. + NaCN CH, CN + Nal DMSO CH3-1 + NaCN C H, CN + Nal Cho (c) CH,0 + CH,CH,Br - HƠ + CHỊCH,Br CH,CH,OCH, + Bril CH,CH,OH + Br...
Substitution Problems I. In each of the problems below, label the alkyl halide as primary, secondary, or tertiary. Labe...
Substitution Problems I. In each of the problems below, label the alkyl halide as primary, secondary, or tertiary. Label the nucleophile as strong or weak. Decide whether an SN2 or an Sy1 reaction occurs. After, show the mechanism and product or products. Indicate stereochemistry where appropriate. a. Reaction of 1-bromopropane and sodium methoxide in methanol CH3 Na CH,Oн Br b. Reaction of 2-bromopropane in ethanol CH3CH2OH Br c. Reaction of (R) 3-chloro-3-methyl heptane in acetic acid Ci Cн CH,COOH но...
09 Which is the major product of the following substitution reaction? CH₂CH₂OH NaBr ? A) CH₃ CH₂ Br D) All of the Above B) CH₃ CH₂ Na E) None of the Above c) CH₂-E-H 20 Which is the major product of the following sultitution reaction? CH₃ CH-CH-CH2 HBr ? OH CH₂ C) CH C=CH-CH₂ A) CH₂ CH-CH=CH₂ Br CH3 Br B) CH₂ C-CH₂=CH₂ D) None of the Above 2 Which is the major product of the following reaction? CH3 PBra...
is the major product of the following substitution reaction! CH₂CH₂OH NaBr ? A) CH₃ CH₂ Br D) All of the Above B) CH₃ CH₂ Na E) None of the above c) CH3-C-H 20 Which is the major product of the following substitution reaction? ? CHICH-CH-CH2 HBr CH OH CH₂ C) CH₂ C=CH-CH₂ Shy A) CH₂ CH-CH=CH₂ D) None of the Above. B) CH₃ ¢-CH₂-CH₃ Br 2) Which is the major product of the following reaction? CH3 CH PBr3 ? CH₂...
1. How many moles of NaBr will be produced by the following reaction in each case? Na(s) + Br2() →NaBr (s) a. 1 mol Na and 0 mol Br2 b. 2 mol Na and 1 mol Br2 c. 3 mol Na and 1 mol Br2
the following compound is
9 Which is the major product of the follow CHOCH, OH NaBr ? of the following substitution reaction? D) All of the Above E) None of the Above A) CH₃ CH₂ Br B) CH3CH(Na, c) CH₂-E-H 20 Which is the major product of 5 CHA CH=CH-CH2 HBr ? the following substitution reaction? major product of CHE OH SHA A) CH₂ CH-CH=CH3 CH2 () CH3 C=CH-CH2 B) CH3 C- CH₂ - CH3 D) None of the Above...
please explain
Identify the product of the following reaction: Br Br ONa САНаО2 2 NaBr NaO Product: Edit
Question 19 What is the product of the following reaction? excess HBT Br OH OH Br ОН ОН Br Br Moving to another question will save this response. A Moving to another question will save this response. Question 20 What is the product of the following reaction? NaBHA ОН ОН A Moving to another question will save this response. A Moving to another question will save this response. Question 22 What is the starting material for the following reaction? 1....
The following reaction is a single-step, bimolecular reaction: CH, Br+ NaOH → CH,OH + NaBr When the concentrations of CH3Br and NaOH are both 0.200 M, the rate of the reaction is 0.0040 M/s. (a) What is the rate of the reaction if the concentration of CH3Br is doubled? Number MIS (b) What is the rate of the reaction if the concentration of NaOH is halved? Number M/s (c) What is the rate of the reaction if the concentrations of...
7 the following substitution reaction? Which is the major product of the follow CHOCHOH NaBr ? A) CH₂ CH₂ Br B) CH CH. Na c) CH₂-E-H D) All of the Above E) None of the Above of the following substitution reaction? CHE is the major product of the following substitut CH₂CH=CH-CH2 HBr ? CHz CÓ CH2=CH-CH3 OH A) CH₂CH=CH-CH3 B) CH3C-CH₂-CH3 D) None of the Above ? Which is the major product of the following reaction? PBra ? CHCH OH...
the weakest base: CH3 HO HS the fastest in an Syl reaction: (CE)_CACHOSCH (CH3CB (CH.) CHCH(Br)CH, (CH),C(Br)CH (CH3)2CHCH Br 2. For each pair of reactions given below indicate which is faster and explain your reasoning. + CHỊ N + C CH3Cl + N CH3 + Ng CH₃N₂ + i CHg. + NaCN CH, CN + Nal DMSO CH3-1 + NaCN C H, CN + Nal Cho (c) CH,0 + CH,CH,Br - HƠ + CHỊCH,Br CH,CH,OCH, + Bril CH,CH,OH + Br...
Substitution Problems I. In each of the problems below, label the alkyl halide as primary, secondary, or tertiary. Label the nucleophile as strong or weak. Decide whether an SN2 or an Sy1 reaction occurs. After, show the mechanism and product or products. Indicate stereochemistry where appropriate. a. Reaction of 1-bromopropane and sodium methoxide in methanol CH3 Na CH,Oн Br b. Reaction of 2-bromopropane in ethanol CH3CH2OH Br c. Reaction of (R) 3-chloro-3-methyl heptane in acetic acid Ci Cн CH,COOH но...
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