propose a mechanism: SN1 1-chloro-1-methylcyclohexane is boiled in ethanol to produce the following compound:
1. Using the reaction of 2-chloro-1-methylcyclohexane with hydroxide ion, give the mechanism of Sn1 substitution. Complete the question as in question 1 2. Show how you might synthesise the following compounds given the indicated starting materials and anything else you need. In other words, show the reactions that would lead from starting materials to products. Assume that you can purify the products of each reaction. A synthesis may require more than one reaction (products of one reaction are used as starting materials in the...
4. Propose two synthetic routes to trans-1-methyl-2-(methylthio)cyclohexane (below) from the starting compound (a) cis-1-chloro-2-methylcyclohexane; (b) trans-1-chloro-2- methylcyclohexane. SCH CH3 5. Rank each of the following groups of substrates in order of decreasing S 2 reactivity. a. b. C. CHỊCH,CH,CI, CHÚCI, (CH, CH) CHOI (CH3),CHCH,CH,Br, (CH3),CHCH,Br, (CH3),CHBr CHỊCH,CI, CH, CH,I, (CH,),CHCl, CH2CH2Br
Draw the detailed SN1 mechanism for the reaction between 2-methyl-2-butanol and HCl to produce 2-chloro-2-methylbutane. 1. Draw the detailed Sn1 mechanism for the reaction between 2-methyl-2-butanol and HCl to produce 2-chloro-2-methylbutane. (3 pts)
What product(s) are expected in the ethoxide-promoted ?-elimination reaction of 1-chloro-1-methylcyclohexane? Omit ions, salts, and ethanol from your response. What product(s) are expected in the ethoxide-promoted beta-elimination reaction of 1-chloro-1-methylcyclohexane? Omit ions, salts, and ethanol from your response.
For each compound listed below, predict the dominant mechanism for each reactant (SN1 and/or SN2). The test reagent mixture you will be using is silver nitrate (AgNO3) in ethanol. Note: a compound may not react at all or react under both mechanisms. If both mechanisms are possible, one is usually dominant. Indicate that where applicable. 1. bromobenzene 2. bromocylopentane 3. bromocyclohexane 4. 2-bromobutane 5. 2-chlorobutane 6. 1-chloroporpan2-one 7. 1-chlorobutane 8. 2-chloro-2-mehtylpropane 9. 1-chloromethylbenzene
Complete the mechanism for the solvolysis of 1-chloro-1-phenylethane in water under SN1 conditions by drawing in the curved arrows where needed.
For each compound listed below, predict the dominant mechanism for each reactant (SN1 and/or SN2). The two test reagent mixtures you will be using are sodium iodide in acetone and silver nitrate in ethanol.Note: a compound may not react at all or react under both mechanisms. If both mechanisms are possible, one is usually dominant. Indicate that where applicable. Reactant KI/acetone AgNO3/ethanol 1 bromobenzene 2 bromocyclopentane 3 bromocyclohexane 4 2-bromobutane 5 2-chlorobutane 6 1-chloropropan-2-one 7 1-chlorobutane 8 2-chloro-2-methylpropane 9 1-chloromethylbenzene
find products for the following interactions and identify the mechanism as sn1, sn2, e1, or e2 A) 2-Iodo-2-phenyl butane + water CH3-CHO-Na+ / ethanol B) 2-Chloro-2-methyl propane + СН3 H3C CH C) 1-Chloro pentane + Nal / acetone + Concentrated H.SO. (No Water added) -----> D) 2-phenylbutan-2-ol ОН 10 pts) E) Write a complete mechanism for Reaction D above Be sure to show the intermediate or transition state.
Provide an SN1 mechanism for the synthesis of tert-pentylchloride (2-chloro-2-methylbutane).
7. Predict the SN2 product of this reaction: NaOH CHOH 8. 1-bromo-2-methylcyclohexane reacts via an SN1 mechanism to produce 2 products. Draw the carbocation intermediate that led to each individual product. Qarakia