Question

A two-arm, randomized, double-blinded trial tested the efficacy of an experimental cancer treatment (Tx), in terms of tumor shrinkage (“response”). A total of 800 cancer patients were randomized either to Tx (n = 400) or to control (n = 400). At the end of a 2-year follow-up period, a total of 225 patients responded in the Tx group while 200 responded in the control group (56.25% vs. 50.00%, chi-square test p = 0.08).

1.Compute either the relative risk (RR) or the odds ratio (OR) to estimate the treatment effect of Tx.

2.Interpret the effect estimate and chi-square test p-value to briefly explain whether or not the study shows that Tx has an effect.

Answer 1

Hre we れ .Cqi Haiyanj ths given in- Control oh a 225 lot 225 X200 bc 45000 35000

225 225t 2 0.5 3 ure 29° n effect on Canter