1) Predict the products for the following reactions or provide reagents. 1. LDA, THE b) Chloroquine...
ROBLE Predict the major products of the following reactions 22-5 (a) acetone )LDA (2) CH2-CHCH2Br (1) LDA (2) CH3I (1) LDA (2) CH3CH2I ROBLE Predict the major products of the following reactions 22-5 (a) acetone )LDA (2) CH2-CHCH2Br (1) LDA (2) CH3I (1) LDA (2) CH3CH2I
Provide the products for the following reactions: 1. LDA, THF, -78 C 1. LDA, THF, -78 C a yoyo a la misma 0 2. VI NaOCH3, CH3OH 1 eq. 2. H30*. H20
1) Predict the product(s) or provide reagents for the following reactions. For products, clearly show stereochemistry. If the enantiomer also forms, write + E. MORE THAN ONE STEP MAY BE REQUIRED. If more than one step is required, number individual steps.
2. (16 pts) Reactions Provide reagents, products or starting materials for the following reactions. Show stereochemistry when relevant (or loss thereof). If a reaction produces no significant products, write "NR". If you have a question about an abbreviation, just ask. NaBr OH 1. TsCI 2. Nal, DMF CI DMSO OH 1. PBrg NaCN 2. KOC(CH3)3 Ether LDA НОН THE NaH NaH PO Acetone Heat, water
Predict the Products/Reagents. Draw the expected products from the following reactions or fill in the missing reagent(s). Where a stereocenter is created, indicate the configuration of the product. Predict the Products/Reagents. Draw the expected products from the following reactions or fil in the missing reagent(s). Where a stereocenter is created, indicate the configuration of the product Br Mgo Et20 8. 1. PhCH2Br 2. BuLi PPh3 9. H2N Et, (c CO2Et Ph 10. NH2 NaBH3CN
Provide the missing reagents, products in the following reactions.
1. Provide the major products for the following reactions. (5) CH3ONa CH3! 1. LDA. -78 deg 2. (CH3)2 Sici @ 2% NaOH CH3OH, heat @ C=0 HCI coEt NaOEVETOH H30*heat Br Br CO,Et
3. Provide the intermediates/products for the following reactions. 3. Provide the intermediates/products for the following reactions 1. BH3. THF 2. H20s NaOH, H2O CH3 1·LDA,-78°C, THF 4. H2O 1. Na CroO HSO, HO 2. SOCl2 Bn
Provide the missing substrates, products, reagents, in the following reactions. Indicate the stereochemistry where appropriate. 7. (36 points) Provide the missing substrates /products/reagents in the following reactions. Indicate the stereochemistry where appropriate. a. HgC﹀CH3 (1) 03 Ph︿H (2) (CH3)2S b. H2 OsO4 PhCH2CECCH2CH3 2r3 Lindlar catalyst t-BuoOH C.
1. a. Provide the reagents necessary to produce the following products, or b. One of these products forms preferentially at low temperature, the other at high temperature. Explain. 2. Propose structures for compounds B and C for the following reactions. Indicate the mechanism for the formation of compounds B and C. NaOCH2CH3 CHCHCHBr H2O+, A B A