2. (16 pts) Reactions Provide reagents, products or starting materials for the following reactions. Show stereochemistry...
what products will the following reactions form? F3C-S 1. Nal, Acetone 2. NaCN, DMF 1. Nal, Acetone 2. CH3CO2Na, CH3CO2H a. NaH, THF OH b. O=SHO
1. Determine whether the following reactions go through SN or SNP and write the products, with stereochemistry as applicable. BrNHz NaOEt Nal OMS KCN CI DMSO Br HO NaSH DMSO Tso CH3 Nal Acetone CH3 2. The following reactions each undergo SNmechanisms. For each explain why you would predict the substitution products to come from an SN2mechanism and fill in the product. If stereochemistry is given in the reactants, give the correct stereochemistry in the products. Cl + Z Na...
12. REACTIONS: Give the MAJOR organic products of each of the following reactions. India stereochemistry where appropriate. [3 points each] 1) NaH 2) CH-CH2 CH,CH,OH HASO. PBrg 1) BH, THE 2) H202 / OH 1) TCI. pyridine 1) NBS 2) DMSO,H2O
4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry. 4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry. NaSCH3 CH3SH (b) - Se(CH3)2 DMF SelfH3)2, con "ayam HD M NaOH sH - hint: product has a S atom in a ring (d) ethanol fone come NaCN acetone CH3 ci+H 1 eq. NaN3 DMSO HOH CH3
Problem 10. Draw the structure of the major product formed in each of the following reactions. Consider the resulting stereochemistry of the products formed (6p) KBr ng MeOH NaF DMSO H2(g), Pd (cat.) c) Solvent OH 1) NaH (strong base) THF (solvent) d) 2) CI Nal e) CI Acetone
4. Reactions Provide the major products for the following reactions. Include Stereochemistry where relevant where no reaction, occurs, write NR. Bra FeBrz 0 CH3 CI OH AIC3 NEC Fell H2O H₂SO4
6. For the following reaction, please draw the reaction mechanism given the starting material, reagents, and product. Include all important intermediates and use curvy reaction arrows to show the flow of electrons. • Nah 2. CI. CN 3 Nah CN 7. For the following starting material A, draw the products Band C that you expect to form under the following reaction conditions. LDA KOC(CH3)s THE 0 B (CH3),COH cold temps room temp A
Unit 3 Hinw '3 SNİSNDELE2 1. Give the major product(s) for the following reactions. Indicate the mec reaction occurs, write "no reaction. s) in operation. If no KOC(CH) (CH COH b. H3C NaNH2 NHy Nal H3C H2CH-CH3 CH,COCH CH OH CH3 2. Give the mechanism of each of the following reactions. NaCN CH CH CHCN NaBr a. CH,CH,CH Br acetone HSCH,CH (CH) CSCH,CH3 HBr Cl + NaCI + CH OH NaOCH CH3OH Br CH OH CH3
1. (20 points) Provide the products for the following reactions. Provide stereochemistry where necessary. Determine whether they are SN2, S1, E2, E1, or Elcb where necessary. NO NEED FOR MECHANISMS. Br NaOCH.CH diethyl ether KOBU DMSO heat NaCN THF
VI. Reactions (21 pts) Provide the major product in the following reaction. If no reaction occurs, write "NR as the product. Show your work for each step!! Pay attention to Regiochemistry and Stereochemistry! TSCI EtyN 1. CHg-Br (xs) 2. Ag20, H20, A H-CI Et20 Sold lo no? NaBH CN a. NaNg, EtOH b. H20,4 OH 1. SOCI, pyridine 2. NaN, DMF 3. LIAIH, Et20