Question

what products will the following reactions form?

F3C-S 1. Nal, Acetone 2. NaCN, DMF 1. Nal, Acetone 2. CH3CO2Na, CH3CO2H a. NaH, THF OH b. O=SHO

Answer 1

0-$-CE + NOS CF3 Na I Acetone, I + Not Hal SN2 reaction Inversion at chiral center Bakside attack CN Hili Nach DMF + NaI Inversion at chiral center Backside N + Na Nach attack SN² reaction Note two consequtive Inversion Net Retention CH3 a Dallel Hoca - H₂ Cara chair conformation diaxial Ella Trans diequitorial con format Cis -4,3 disubstituted cyclohexane cis Less stable more stable AI Nal Acetone T I Inversion at chiral CH3 Center I 't Nous Nai SN² Reaction. CH3 o back side attack -CH3 onze CH3 Coona, CH3 Cool + CH₃Coona 2 & Na a CH Inversion. so-ceta + Ha Back side SN2 e Back side Reaction attack

Backside attack SN² reaction V on Nalt NaIT Ether'