What is the major product in each of the S 2 reactions below? For each product,...
What is the major product in each of the S2 reactions below? For each product, label all stereocentres as R or S as appropriate. [8 Marks] CI CH2CH2SNa acetone 1. Nah in THE no on 2 1. NaH in THE CH3 HBr H+CH3 CH2CH3 NaCN acetone
What is the major product in each of the SN2
reactions below? For each product, label all
stereocentres as R or S as
CH3CH2SNa acetone 1. NaH in THF 2. 1. NaH in THF HS 2.
4. Give the major organic product(s) for each of the following reactions or sequences of reactions. H Br 1. N.CN 2. NaOH,H,O, heat 3.H30 Ind o do CH,COOH 1. LiAlH, THF, heat 2.H,0 HO CH Br 1. NaCN, acetone 2.H30, heat h ome couco C:03, H30* он
what are the major products of these reactions
38. what is the major organic product of the following reaction? ? CH3CH NHCH2 CH3 -N-C2Hs С,н, IV N СH, I. CH2CH3 он п. -СHs N C2H ш. =N-C,Hs сHя 39. what is the major organic product of the following reaction? H2 CH3CH2NH2 Pt CH2CH3 он I. IV. NHCH,CH3 NCH,CH3 П. NHCH,CH3 V. CH2CH3 ш.
4. (12 marks) For each of the following reactions, predict the
MAJOR product with correct stereochemistry.
4. (12 marks) For each of the following reactions, predict the MAJOR product with correct stereochemistry. NaSCH3 CH3SH (b) - Se(CH3)2 DMF SelfH3)2, con "ayam HD M NaOH sH - hint: product has a S atom in a ring (d) ethanol fone come NaCN acetone CH3 ci+H 1 eq. NaN3 DMSO HOH CH3
17. Draw the structure of the major organic product(s) for each of the following reactions. Indicate stereochemistry when appropriate. C(CH3)3 NASH Br (S)-2-bromononane - acetonitrile KOH CH,OH NaCN HE Br Acetonitrile C2H5 H, Br NaOH Acetone excess HBr ROOR HC1 + Br Na o DMSO
For the following reactions, predict the MAJOR product(s). If a pair of enantiomers is expected, draw both enantiomers. NaSH Cis-1-bromo-3-methylcyclohexane acetone OTs 1. NaI/acetone 2. NaCN/DMF CH3 NaCN H,с. Br CH3 Бшн.
Provide the major organic product (including stereochemistry if appropriate) for each of the following reactions: 3. 1) NaH а) (CH)-СHCH,ОН 2) (CH),СНОСH-CH,Br b) excess HI 1) Hg(OAc),/H,O 2) NaBHĄ/HO¯ 1) NaOH 2) PҺOH d) CH,CH,Br 1) BH3/THF 2) H-0,/Но" НCIZnClz он g) MCPBA h) 1) mCPBA 2) CH3O¯ 1) mCPBA 2) CH,ОН/Н"
Part II - Reactions (16 marks] Draw the expected major product(s) for each of the following reactions. Question Answer 8. 1. NaH OH ? 2. OTs 9. NBS ? major product 10. Nal Br ? Acetone Br 11. 1. NaNH2 H3C-CECH ? 2. OTS 12. OH Br NaOH ? cyclic compound 13. OH HBT ? 14. ? OH cat. H2SO4 H20 Room temp. 15. Br MeOH
What major Organic product is formed after the following sequence of reactions? 1) NaH, THF 2) Br Br B1 (C) (b) Br Bi a. a Considering both regiochemistry and stereochemistry, what is the major Organic product of the following reaction? о ні. CH-CH, НСІ Снон HC "CH; но CH, НО CH, HCO CH-CH; CH «CH-CH, OCH; CH CH3 ОН нс СІ H; Н;С (6) (c) H.CO CH, Kotic CH.CH НО CH; Но CH.CH Сн, НП). CH,CH; ОН нс Н.С осн;...