Question

1. (20 points) Provide the products for the following reactions. Provide stereochemistry where necessary. Determine whether they are SN2, S1, E2, E1, or Elcb where necessary. NO NEED FOR MECHANISMS. Br NaOCH.CH diethyl ether KOBU DMSO heat NaCN THF

Answer 1

The answer is explained in the given image as it involves drawing of chemical structures.

10 s-bydwyrardough Base catalyzed deluy duration of a nyang the ExcB pathway. This is because the conjuge X-B-unsel wrated carbonyl ed doby obration of p-hydroxycarbonyl follows d. This is because the conjugate base is 7 Stabilized by evolote out Nabet (b) Br Etzo This is SN² reaction, as the carbo carbon stereochemistry not rego centre is achiral Hon , as the carbon is a primary stereocha mishy not read. as the reaction ce) КОЕВи Ez-elimination non polar solvent DMSO (solvent) There are 2-possible centres from where the base can abstract & But kot Bu is a bulky base, and is abstracts proton from the less sterically hindered position .. Moreover, the criteria of elimination is that the proton and the leaving group should be antiperoplanar from the stereo chourishy Shocin only one centre satisfies Hue condition NaCN HUN SN² reaction OTOS ТИЕ (solent) in moderately polar aprotic solvent Stereo chenustry: Inversion of configuration. -otos is a very good leaving group.