2.List five ways in which the activity of importin/exportin can be attenuated.

Question

Question

Answer 1

Answer #1

Activity of exportin and importin can be reduced or attenuated:

exportin and importin proteins are used to export and import the peptides from the nucleus with the help of other proteins. Activity of exportin and importin can be attenuated if there is a mutation in the gene which codes for exportin and importin.
Alteration in the binding site of the exportin and importin .
Alteration in the signal peptide that bind to the exportin and importin.
Mutation in GTP binding site.
requirements of other helping proteins ( ranGAP in the cytoplasm and ranGEF in the nucleus ).

Answer 2

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