Would a cell that was missing the kinetochores on one of its chromosomes be able to...
Would a cell that was missing the kinetochores on one of its chromosomes be able to get past the metaphase checkpoint?
No, because kinetochores are necessary for sister chromatids to be held together.
No, because the spindle could no attach to that chromosome and pull it to the midline
No, because cohesin on the chromosome could not dissolve
Yes, because the kinetochores do not have any effect on the metaphase checkpoint.
Homework Answers
kinetochores are protein complex on the chromosome at the centromere where the mitotic spindle attaches, mitotic spindle attaches to the chromosomes during prometaphase and align the chromosomes on the metaphase plate if the kinetochores are missing mitotic spindle cannot attach to the chromosomes and align it to the metaphase plate, so the cell cannot pass metaphase checkpoint.
cohesin holds two sister chromatids, cohesin protein is degraded during anaphase to separate sister chromatids.
b) No, because the spindle could no attach to that chromosome and pull it to the midline
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Would a cell that was missing the kinetochores on one of its
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