Question

4. (3pts) Consider the following four substrates (i-iv). Fill in the the bubble that places them in order of increasing rate of reaction with Nal in acetone solvent. This means the number "1" is placed under the substrate that reacts the slowest. into the iv Br O O O O iv <ii <i<iii iii <i<i <iv iii <iv <ii si iv <ii < iii <i None of the above

Answer 1

Order of Reactivity of alkyl halides in SN2 reaction is Primary alkyl halide > Secondary alkyl halide > Tert alkyl halide i. Br A primary alkyl halide. So it is more readive in SN2 so order = 4 ii, Br Primary alkyl halide with steric hindrance so it is less readive than above compound so order = 3 Sec alkyl halide so it is less readive than above two compounds order = 2 ii. L ow OH it It is an alcohol. alcohols can not under go SN2 reaaction. since OH is not a good leaving Order = 1 so Order iii < i <ji<i Loyiha mer