Question

allele for achromatopsia so prevalent in this population u ule typhoon and famine represent? What has made the frequency of tne gene pool after the typhoon 5. Most of our DNA sequence is identical, however there are places in the genome quence can vary from person to person. These variations are where thee sts use one type of highly variable polymorphisms for DNA analysis. STRs (short called polymorphisms. Forensic em repeats) are short (2-5 bp) sequences of DNA that are repeated. The variation the number of repeats, and the variation is inherited with homozygous and heterozygous is found in genotypes For instance one of these sites is found on chromosome #7, and it is called D75280-A GATA is repeated. An example of a "genotype" that would be written is 10,14 n chromosome #7 at that site the individual has 10 repeats of GATA, on the other chromos this site ome #7 they have 14 The number of repeats can vary tremendously, making STR sites useful in trying individuals by comparing DNA from crime scenes with DNA from suspects. question however. If there is a match, what is the chance th same repeat that include the allele frequencies for each STR locus used to identify There is always a at there is another individual with the genotype? In order to answer that question, population databases must be created a. An individual has the genotype 15,18 at the D3$1358 locus. In a reference database of 200 aucasians, the frequency of the 15 allele is 0.285, and the frequency of the 18 allele is U.S. C 0.1450. What is the frequency of the heterozygous 15,18 genotype? DIS 1656 |D25441.1 D2S1338 ТРОХ D3S1358 LFGA DSS8181 SFIPO D7S820 D8S1179 Locus 17,23 3.9% 15,18 8.2% 11,13 13% 72% 6.3% 9.9% 2% 3.52% 1.7% D10S1248 TH01 9,9.3 9.6% VWA D12S391 D13S317 D16S539 D18S51D19S433 D21S11 D22S1045 16,16 Locus 29,31 4.3% 13,15 3.1% 1.2% 9.5% 4.3% requ In order to increase the accuracy of forensic DNA analysis worldwide, 20 different STR sites are examined. To determine the frequency of the "DNA profile" the frequency of each of the 20 genotypes are multiplied. The answer gives you what is called the "random match probability" - the chance that there is another person in the population with the same profile. Note: The current world population level is 7.2 billion What is the random match probability for the DNA profile in the above table? Would this outcome be useful in a court of law to identify with 100% certainty and individual who committed a crime? State your opinion. b.

Answer 1

a.)16.53 is the genotypic frequency (2×pq×200)

b.)The Random match probablity is 2.822052015754E−28 obtained by multiplying the frequencies of all the locus.Yes it detmines the factor of determination of guilty and evidence