Protein kinase A phosphorylates _____, which then activates _____. A) phosphorylase kinase; glycogen phosphorylase B) protein...
Protein kinase A phosphorylates _____, which then activates
_____.
| A) phosphorylase kinase; glycogen phosphorylase |
| B) protein phosphatase 1; glycogen synthase |
| C) glycogen phosphorylase; phosphoglucomutase |
| D) adenylate cyclase; phosphorylase kinase |
Homework Answers
Option A is the correct answer that is protein kinase A phosphorylates phosphorylase kinase, which then activates glycogen phosphorylase.
Option B, C and D are wrong because they are activated by other protein kinase but not protein kinase A.
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Protein kinase A phosphorylates _____, which then activates
_____.
A) phosphorylase kinase; glycogen phosphorylase
B) protein...
Which is not involved in the regulation of glycogen phosphorylase? A) Allosteric inhibition of phosphorylase by...
Which is not involved in the regulation of glycogen phosphorylase? A) Allosteric inhibition of phosphorylase by ATP B) Indirect, positive regulation by glucagon C) Phosphorylation of phosphorylase by protein kinase A (PKA) D) Direct and indirect regulation by protein phosphatase 1 (PP1) E) Indirect, negative regulation by protein phosphatase 2B (PP2B)
Arrange in proper order the events of the signal-transduction cascade for glycogen degradation in muscle. Muscle...
Arrange in proper order the events of the signal-transduction cascade for glycogen degradation in muscle. Muscle contraction begins. Phosphorolysis of glycogen yields glucose l-phosphate. Answer Bank Phosphorylase kinase is phosphorylated on its and a subunits. Intracellular CAMP levels increase, which activates protein kinase A. Epinephrine is released and binds to muscle ß-adrenergic receptors. The stimulatory G, protein dissociates and activates adenylate cyclase. Phosphorylase kinase is partly activated by binding Ca2+ Glycogen phosphorylase b is converted to glycogen phosphorylase a.
In muscle tissue, the ratio of phosphorylase a to phosphorylase b determines the rate of conversion of glycogen to gluco...
In muscle tissue, the ratio of phosphorylase a to phosphorylase b determines the rate of conversion of glycogen to glucose 1-phosphate. Classify how each event affects the rate of glycogen breakdown in isolated muscle tissue. Increased rate ; Decreased rate ; No change Option: addition of phosphorylase b kinase ; addition of a phosphatase inhibitor ; end of fight-or-flight response ; treatment with glucagon ; AMP allosteric binding activates phosphorylase b ; treatment with insulin ; addition of phosphatase PP1...
Which statement is true? Epinephrine activates glycogen phosphorylase. Epinephrine increases glycolysis in muscle. Insulin decreases glycogen...
Which statement is true? Epinephrine activates glycogen phosphorylase. Epinephrine increases glycolysis in muscle. Insulin decreases glycogen breakdown by increasing phosphoprotein phosphatase-1 activity. All of the above
1. Which of the following is true regarding glycogen metabolism? a. Glycogen synthase is activated by...
1. Which of the following is true regarding glycogen metabolism? a. Glycogen synthase is activated by phosporylation. b. Glycogen phosphorylase kinase activates glycogen phosphorylase through phosphorylation. c. The activation of PKA is downstream of insulin signaling in muscle cells. d. Glycogen phosphorylase releases free glucose from the ends of glycogen.
2a. What converts glycogen synthase into the alpha form after exercise? a. previous emission of..
2a. What converts glycogen synthase into the alpha form after exercise? a. previous emission of epinephrine b. protein kinase A c. glycogen synthase kinase (incorrect) d. phosphorylase e. protein phosphatase 1 2B. Where can oxidative phosphorylation take place in living organisms? Select all that apply. a. plasma membrane b. inner membrane of mitochondrion c. cristae d. mitochondrial matrix e. cytoplasm
1. An enzyme that phosphorylates nucleotides is c. phosphofructokinase b. phosphorylase d. succinyl-CoA synthetase a. malic...
1. An enzyme that phosphorylates nucleotides is c. phosphofructokinase b. phosphorylase d. succinyl-CoA synthetase a. malic enzyme 2. An example of a nucleotide-regulated allosteric enzyme is a. lactonase c. pyruvate kinase b. alcohol dehydrogenase d. enolase 3. Adenylate kinase makes ATP and AMP b. ATP only a. c. ADP and AMP d. AMP only
12. An enzyme, phosphodiesterase, catalyzes the conversion of CAMP to AMP. Using the glycogen control diagram...
12. An enzyme, phosphodiesterase, catalyzes the conversion of CAMP to AMP. Using the glycogen control diagram handed out separately, predict whether activating phosphodiesterase in turn activates or deactivates each of the enzymes below: Deactivates Activates Enzyme phosphorylase kinase glycogen phosphorylase phosphoprotein phosphatase-1 glycogen synthase ロロロロ ロロロロ Thus, when phosphodiesterase is activated, glycogen degradation is glycogen synthesis is activated Odeactivated and O activated Odeactivated. Based on your answers above, which hormone most likely activates phosphodiesterase? Check all that apply. O insulin...
Place in the right order the sequence of biochemical events between the release of epinephrine by...
Place in the right order the sequence of biochemical events between the release of epinephrine by the adrenal glands and the breakdown of glycogen in the liver. (1) Epinephrine is released by the adrenal glands. ( ) Activated beta-adrenergic receptors cause GTP for GDP exchange in the alpha subunits of Gs G proteins ( ) The activated catalytic subunits of PKA phosphorylate the inactive phosphorylase kinase b, activating it. ( ) Epinephrine travels in the bloodstream ( ) Two cAMP...
, ras-, Rat-, MEK-, MAPK. / 4. What determines the sensitivity of a cell to a...
, ras-, Rat-, MEK-, MAPK. / 4. What determines the sensitivity of a cell to a signaling ligand? a. The number of receptor proteins in the plasma membrane. b. The ligand concentration. c. The Kd of the receptor for a ligand. d. All of the above e. None of the above. 5. In the "fight or flight" response, epinephrine stimulation of muscle cells: a. inactivates Glycogen Phosphorylase Kinase (GPK). b. inactivates Glycogen Synthase (GS) c, activates Phosphoprotein Phosphatase 1 (PP1)....
Arrange in proper order the events of the signal-transduction cascade for glycogen degradation in muscle. Muscle contraction begins. Phosphorolysis of glycogen yields glucose l-phosphate. Answer Bank Phosphorylase kinase is phosphorylated on its and a subunits. Intracellular CAMP levels increase, which activates protein kinase A. Epinephrine is released and binds to muscle ß-adrenergic receptors. The stimulatory G, protein dissociates and activates adenylate cyclase. Phosphorylase kinase is partly activated by binding Ca2+ Glycogen phosphorylase b is converted to glycogen phosphorylase a.
1. An enzyme that phosphorylates nucleotides is c. phosphofructokinase b. phosphorylase d. succinyl-CoA synthetase a. malic enzyme 2. An example of a nucleotide-regulated allosteric enzyme is a. lactonase c. pyruvate kinase b. alcohol dehydrogenase d. enolase 3. Adenylate kinase makes ATP and AMP b. ATP only a. c. ADP and AMP d. AMP only
12. An enzyme, phosphodiesterase, catalyzes the conversion of CAMP to AMP. Using the glycogen control diagram handed out separately, predict whether activating phosphodiesterase in turn activates or deactivates each of the enzymes below: Deactivates Activates Enzyme phosphorylase kinase glycogen phosphorylase phosphoprotein phosphatase-1 glycogen synthase ロロロロ ロロロロ Thus, when phosphodiesterase is activated, glycogen degradation is glycogen synthesis is activated Odeactivated and O activated Odeactivated. Based on your answers above, which hormone most likely activates phosphodiesterase? Check all that apply. O insulin...
, ras-, Rat-, MEK-, MAPK. / 4. What determines the sensitivity of a cell to a signaling ligand? a. The number of receptor proteins in the plasma membrane. b. The ligand concentration. c. The Kd of the receptor for a ligand. d. All of the above e. None of the above. 5. In the "fight or flight" response, epinephrine stimulation of muscle cells: a. inactivates Glycogen Phosphorylase Kinase (GPK). b. inactivates Glycogen Synthase (GS) c, activates Phosphoprotein Phosphatase 1 (PP1)....
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