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What is the inbreeding coefficent of person I in the following pedigree? Assume that the inbreeding coefficent is O for anyon
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Answer #1

The general formula for the coefficient of inbreeding is F = Σ[(0.5)n(1 + FA) where Σ is the sum of the paths through which an individual can derive identical alleles from his ancestors and n = the number of individuals  in the paths and

FA is the inbreeding coefficient of the common ancestors

lets how find the allele common ancestors of I and pass from top to bottora. 77 Black and red lines indicate the two path thrF= {(o.s) (1+FA) In the question it is mentioned to consider, FA as zero. UP So F= (0:57C140) + (053C1+0) = 0.008 +0.008 = 0.

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