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1. Down syndrome is due to a. nondisjunction of chromosome 21. O b. nondisjunction of the...
19) Trisomy 21, or Down syndrome, occurs when there is a nom complement but one (extra)...
19) Trisomy 21, or Down syndrome, occurs when there is a nom complement but one (extra) chromosome 21. Although fertility is reduced in both sexes, females have higher fertility rates than males. Van Dyke et al. (1995; Down Syndrome Research and Practice 3(2):65-69) summarize data involving children born of Down syndrome individuals. Assume that children are born to a female with Down syndrome and a normal 46-chromosome male. What proportion of the offspring would be expected to have Down syndrome?...
Down syndrome, or trisomy 21, in humans is caused by an extra copy of the relatively...
Down syndrome, or trisomy 21, in humans is caused by an extra copy of the relatively small, acrocentric 21. Including only chromosome 21, the X chromosome (medium in size and somewhat metacentric) and the Y chromosome (small and acrocentric), draw one possible array of chromosomes in the four sperm cells produced by the complete meiosis of one primary spermatocyte in a male individual with Down syndrome. For the purposes of this question, assume that males with Down syndrome produce normal...
What causes de la Chapelle syndrome (XX male syndrome)? A. It is caused by two nondisjunction...
What causes de la Chapelle syndrome (XX male syndrome)? A. It is caused by two nondisjunction events. The first occurs during meiosis in the mother resulting in an XX egg, and the second occurs during meiosis in the father resulting in a sperm with no X or Y chromosomes. When this sperm fertilizes the egg it results in XX male syndrome. B. SRY is intact but the body is unable to respond to the hormone androgen, which produces the female...
If a person has Down Syndrome (Trisomy 21), then the gamete produced by the mother of...
If a person has Down Syndrome (Trisomy 21), then the gamete produced by the mother of that person had: A. 21 copies of chromosome 3. B. three copies of chromosome 21. C. 24 chromosomes. D. 47 chromosomes.
2. (5 PTS) You are presented with a patient, named Gerry, who has Down syndrome (trisomy 21). You determine that the no...
2. (5 PTS) You are presented with a patient, named Gerry, who has Down syndrome (trisomy 21). You determine that the nondisjunction event occurred in his mother, named Mary, during meiosis I. a. You are interested in the TPTE gene, which is near the centromere of chromosome 21. Virtually no recombination occurs between the centromere and the TPTE gene. Mary has two different alleles of the TPTE gene. Would Gerry's two chromosome 21s from his mother have the same or...
1. DNA testing of an individual with Klinefelter syndrome shows that they are heterozygous at mul...
1. DNA testing of an individual with Klinefelter syndrome shows that they are heterozygous at multiple loci on the X chromosome. At these loci they have one allele that matches their dad's X chromosome and one allele that matches one of their mom's X chromosomes. Did nondisjunction take place during: A) meiosis l in the oocyte B) meiosis l in the sperm C) meiosis l in the oocyte D) meiosis Il in the sperm Diagram meiosis in the affected gamete...
3. Edwards syndrome is caused by an extra chromosome 18. This may result from primary nondisjunction...
3. Edwards syndrome is caused by an extra chromosome 18. This may result from primary nondisjunction during meiosis. The diagram represents such a meiosis beginning with a diploid cell containing synapsed chromosome 18's (a chromosome 18 bivalent) Assuming primary nondisjunction, draw in chromosome 18 in all of the cells shown, and on the lines provided write the chromosome formula (i.e., the n number) and the total number of chromosomes in every cell. For instance, on the lines by the first...
Please show calculation steps for this. Thank you Familial down syndrome is due to a Robesonian...
Please show calculation steps for this. Thank you
Familial down syndrome is due to a Robesonian translocation that fuses chromosome 21 to chromosome 14 (most often). Individuals that have this translocated chromosome but no symptoms of Down syndrome are called translocation carriers. How many chromosomes do translocation carriers have (human diploid cells are typically 2N=46)? If an individual has a Down syndrome caused by the presence of this type of Robesonian translocation, how many chromosomes do they have?
4. A man makes 0 units of an enzyme due to homozygous recessive gene on chromosome...
4. A man makes 0 units of an enzyme due to homozygous recessive gene on chromosome 21. He marries a woman who produces 100 units of the same enzyme due to the heterozygous pairs of genes on her chromosomes 21. Their firstborn son has three copies of chromosome 21 and produces 200 units of the enzyme mentioned above. a) In which parent did the nondisjunction occur? b) Did the nondisjunction occur in meiosis I, meiosis II or mitosis? c) What...
4. A man makes 0 units of an enzyme due to homozygous recessive gene on chromosome...
4. A man makes 0 units of an enzyme due to homozygous recessive gene on chromosome 21. He marries a woman who produces 100 units of the same enzyme due to the heterozygous pairs of genes on her chromosomes 21. Their firstborn son has three copies of chromosome 21 and produces 200 units of the enzyme mentioned above. a) In which parent did the nondisjunction occur? b) Did the nondisjunction occur in meiosis I, meiosis II or mitosis? c) What...
19) Trisomy 21, or Down syndrome, occurs when there is a nom complement but one (extra) chromosome 21. Although fertility is reduced in both sexes, females have higher fertility rates than males. Van Dyke et al. (1995; Down Syndrome Research and Practice 3(2):65-69) summarize data involving children born of Down syndrome individuals. Assume that children are born to a female with Down syndrome and a normal 46-chromosome male. What proportion of the offspring would be expected to have Down syndrome?...
2. (5 PTS) You are presented with a patient, named Gerry, who has Down syndrome (trisomy 21). You determine that the nondisjunction event occurred in his mother, named Mary, during meiosis I. a. You are interested in the TPTE gene, which is near the centromere of chromosome 21. Virtually no recombination occurs between the centromere and the TPTE gene. Mary has two different alleles of the TPTE gene. Would Gerry's two chromosome 21s from his mother have the same or...
1. DNA testing of an individual with Klinefelter syndrome shows that they are heterozygous at multiple loci on the X chromosome. At these loci they have one allele that matches their dad's X chromosome and one allele that matches one of their mom's X chromosomes. Did nondisjunction take place during: A) meiosis l in the oocyte B) meiosis l in the sperm C) meiosis l in the oocyte D) meiosis Il in the sperm Diagram meiosis in the affected gamete...
3. Edwards syndrome is caused by an extra chromosome 18. This may result from primary nondisjunction during meiosis. The diagram represents such a meiosis beginning with a diploid cell containing synapsed chromosome 18's (a chromosome 18 bivalent) Assuming primary nondisjunction, draw in chromosome 18 in all of the cells shown, and on the lines provided write the chromosome formula (i.e., the n number) and the total number of chromosomes in every cell. For instance, on the lines by the first...
Please show calculation steps for this. Thank you
Familial down syndrome is due to a Robesonian translocation that fuses chromosome 21 to chromosome 14 (most often). Individuals that have this translocated chromosome but no symptoms of Down syndrome are called translocation carriers. How many chromosomes do translocation carriers have (human diploid cells are typically 2N=46)? If an individual has a Down syndrome caused by the presence of this type of Robesonian translocation, how many chromosomes do they have?
4. A man makes 0 units of an enzyme due to homozygous recessive gene on chromosome 21. He marries a woman who produces 100 units of the same enzyme due to the heterozygous pairs of genes on her chromosomes 21. Their firstborn son has three copies of chromosome 21 and produces 200 units of the enzyme mentioned above. a) In which parent did the nondisjunction occur? b) Did the nondisjunction occur in meiosis I, meiosis II or mitosis? c) What...
4. A man makes 0 units of an enzyme due to homozygous recessive gene on chromosome 21. He marries a woman who produces 100 units of the same enzyme due to the heterozygous pairs of genes on her chromosomes 21. Their firstborn son has three copies of chromosome 21 and produces 200 units of the enzyme mentioned above. a) In which parent did the nondisjunction occur? b) Did the nondisjunction occur in meiosis I, meiosis II or mitosis? c) What...
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