Question

The effect of exposure to high levels of alcohol consumption was compared to occasional or no alcohol consumption among adult males and females. It is hypothesized that high levels of alcohol consumption is associated with myocardial infarction (MI). This association was studied with 596 incident cases of MI diagnosed in the emergency rooms of several hospitals and compared to 1012 other subjects who visited the same emergency rooms for reasons other than cardiovascular and respiratory diseases. All subjects were asked to report average weekly alcohol intake over the past month prior to their hospital visit. After completing the recruitment, the investigators compiled their data in the following table: Alcohol Consumption Frequent(>2 drinks/week)Occasional (1-2 drinks None (0/week) week 152 Acute MI 283 306 161 262 Other ER Visit 1. What is the study design and appropriate measure of association? (1 point) 2. Calculate the measure of association for those reporting frequent and occasional alcohol consumption as compared to those reporting no consumption over the past month. (2 points) 3. Provide an interpretation of the measures calculated in question 2.(2 point)

Answer 1

Answer:

1.To comprehend the issue appropriately first we have to comprehend the speculation expressed here.

   Alcohol utilization has no relationship with Myocardial Infarction.( MI)

Alcohol utilization has relationship with Myocardial Infraction . (MI)

In this investigation , we need to discover a proportion of relationship between introduction to liquor utilization versus Myocardial Infarction .

Here we use Risk Ratios as a proportion of affiliation taking low liquor utilization as reference amass.

2.

So as to do that we have to look the table along these lines.

		Acute MI	Other ER visit	Total
Liquor consumption	Frequent (>2 drinks /Week)	283	306	589
	Occasional ( 1-2 drinks /Week)	152	444	596
	None ( 0 drinks / Week)	161	262	423

The Cumulative Incidence for successive liquor consumers is given by

= 283/589

= 0.4804

The Cumulative Incidence for Occasional liquor consumers is given by

= 152/ 596

= 0.2550

The Cumulative Incidence for non-consumers is given by

= 161/423

= 0.3806

The hazard proportion for intermittent liquor consumers contrasted with no utilization of liquor ( reference gathering) is given by :

= 0.2550/0.3806

= 0.67

The hazard proportion for continuous liquor consumers contrasted with no utilization of liquor ( reference gathering) is given by :

= 0.4804/0.3806

= 1.2622

3.

The Measure propose that periodic liquor utilization has nearly lower presentation to Myocardial Infarction

than No liquor utilization.

Yet, visit liquor utilization has higher introduction to Myocardial Infarction than No liquor utilization.